Functions of Natural Products in Metabolic Diseases
A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 185
Special Issue Editors
2. Facultad de Ciencias Médicas, Universidad Nacional de la Plata, La Plata 1900, Argentina
Interests: diabetes; prediabetes; metabolic syndrome; liver; natural products
2. Institute of Health Sciences, Arturo Jauretche National University-CICPBA, Florencio Varela, Argentina
Interests: pharmacology of antioxidant; anti-inflammatory; antidiabetes; cardioprotective natural products
Special Issue Information
Dear Colleagues,
In recent decades, the world has witnessed a dramatic increase in the prevalence of metabolic diseases, despite the availability of various pharmacological options for treatment and prevention. While these existing medications play a crucial role, limitations in their use have ignited renewed interest in natural products derived from plants. Advances in technology and the development of new experimental models have fueled this resurgence, particularly in the realm of discovering new drugs for metabolic diseases.
Many ancient medical systems across Asia, Africa, and Latin America have a long history of exploring the therapeutic potential of medicinal plants. However, a significant portion of this vast herbal arsenal remains scientifically unvalidated, hindering its broader recognition by health authorities. This gap presents a missed opportunity, as numerous traditional phytotherapeutic formulations have demonstrated promising preclinical and clinical activity against prevalent metabolic diseases, often through innovative mechanisms of action.
This Special Issue aims to bridge this gap by showcasing recent research advances in utilizing natural products for metabolic disease treatment. It features a selection of articles highlighting both in vitro and in vivo studies that explore the bioactivity of natural products against pathologies such as obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD). By illuminating the scientific basis behind traditional practices and promoting further research, we hope to pave the way for greater integration of natural products into mainstream healthcare systems.
Dr. Flavio Francini
Prof. Guillermo R. Schinella
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- plant natural products
- metabolic diseases
- phytomedicine
- pharmaceuticals
- obesity
- diabetes
- NAFLD
- cardiovascular risk
Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
A Plant-Derived Dissociated Glucocorticoid Receptor Modulator Mitigates Glucolipotoxicity in the Endocrine Pancreas And Liver: Preclinical Data from a Mouse Model of Diet-Induced Metabolic Syndrome
Miranda Sol Orellano1,2, Andrea Scelza-Figueredo1,2 †, Lucía Lameroli Mauriz2,3 †, Carolina Sétula1,2, Milagros Argañaras1, Catalina Atorrasagasti2,3, Marcelo Javier Perone1,2, Luz Andreone1,2.
1 Laboratorio de Inmuno-Endocrinología, Diabetes y Metabolismo, Instituto de Investigaciones en Medicina Traslacional (IIMT-CONICET-Univ. Austral), Pilar, Argentina.
2 Facultad de Ciencias Biomédicas, Universidad Austral, Pilar, Argentina.
3 Programa de Hepatología experimental y terapia génica, Instituto de Investigaciones en Medicina Traslacional (IIMT-CONICET-Univ. Austral), Pilar, Argentina.
† These authors contributed equally to this work.
