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Article
Peer-Review Record

Comparing the Risk of Infusion-Related Reactions and Tolerability in Patients Given Cetirizine or Diphenhydramine Prior to Ocrelizumab Infusion (PRECEPT)

Medicina 2024, 60(4), 659; https://doi.org/10.3390/medicina60040659
by Kyle Smoot *, Horia Marginean, Tiffany Gervasi-Follmar and Chiayi Chen
Reviewer 1:
Reviewer 2:
Medicina 2024, 60(4), 659; https://doi.org/10.3390/medicina60040659
Submission received: 22 March 2024 / Revised: 15 April 2024 / Accepted: 17 April 2024 / Published: 19 April 2024
(This article belongs to the Section Neurology)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

The article presented here is interesting. The study design is solid, and the results are not misleading; they are clearly presented.

I only have minor comments.

I would suggest adding the ethical protocol number in the Materials and Methods sections.

My next comments are about the Discussion section.

I would suggest discussing what would constitute a good scale (sensitive enough) or how to modify the MFIS MSIS-29 to increase sensitivity.

What would you do to enhance the study's power to detect significant differences between groups?

I would also discuss why some patients experience adverse effects.

Finally, I would suggest discussing the limitations of this study and proposing directions for future research.

Thank you

Author Response

See attached word document.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors


Comments for author File: Comments.pdf

Author Response

See attached word document

Author Response File: Author Response.pdf

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