Spontaneous Remission of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report
Abstract
:1. Introduction
2. Clinical Case
3. Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Antibody and Fluorochrome | Clone | Manufacturer * |
---|---|---|
CD16-FITC | 3GB | BD |
CD2-PE-Cy7 | L303 | BD |
CD5-PerCP | L17F12 | BD |
CD4-PE | 13B8.2 | BC |
CD13-PE | L138 | BD |
CD34-PerCP | 8g12 | BD |
CD117-PE-Cy7 | 104D1D2 | BC |
CD11b-APC | D12 | BD |
CD71-APC-H7 | M-A712 | BD |
CD64-V450 | 10.1 | BD |
CD45-V500 | 2D1 | BD |
HLA-DR-FITC/PerCP | DK25//CR3/43 | Palex//BD |
CD123-PE | 9F5 | BD |
CD36-FITC | FAG.152 | BC |
CD33-PE/APC | P67.6//P67.6 | BD//BD |
CD14-APC | M⊘P9 | BD |
CD56-PE/PE-Cy7 | MY31//N901 | BD//BC |
CD15-FITC | MMA | BD |
CD8-FITC | DK25 | Palex |
CD3-V450 | UCHT1 | BD |
cyCD3-V450 | UCHT1 | BD |
cyMPO-PE | _CLB_MPO | BC |
CD19-PerCP | SJ25C1 | BD |
CD20-APC | L27 | BD |
CD22-PE/APC | S_HCL_1 | BD |
CD10-PE/APC | HI10a | BD |
CD38-APC-H7 | HB7 | BD |
cyTdT-FITC | HT-6 | Palex |
cyKappa-FITC | Polyclonal | Dako |
cyLambda-PE | Polyclonal | Dako |
CD7-APC | HIT7 | Immunostep |
CD203c-PE | NP4D6 | BD |
Case Nº | Age/Sex | Sites of Involvement | Phenotype | Karyotipe | NGS | Response (Months) | Trigger Factor before SR | Second Treatment | Survival (mo) | References |
---|---|---|---|---|---|---|---|---|---|---|
1 | 87/M | Skin BM | CD123 CD56 TCL1 CD4 | 46,XY | NA | PR (2 m) | Sepsis | None | 8 (dead) | Suzuki, A, et al., 2021 [16] |
2 | 79/M | Skin | CD4 CD56 | NA | NA | PR | NP | NA | NA | Pemmaraju, N, et al., 2019 [25] |
3 | 78/M | Skin BM LN | CD123 CD56 TCL1 CD4 | 46,XY | NA | 1st PR (2 m) 2nd PR (5 m) | ASR | THP-COP | 18 (dead) | Daitoku S, et al., 2019 [22] |
4 | 15/F | BM LN | CD4 CD56 | 46,XX | NA | PR | NA | Ara-C, VP-16, MIT | 18 (alive) | Hashikawa K, et al., 2012 [24] |
5 | 67/M | Skin Stomach | CD4 CD56 CD123 | NE | NA | CR | NA | None (discharged) | NA | Yasuda H, et al., 2014 [23] |
6 | 40/M | Skin BM | CD4 CD56 CD123 | Complex karyotipe | TP53 KRAS | CR (5 m) | Soft tissue infection | HyperCVAD and aloTPH | 18 (dead) | Present clinical case |
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Castaño-Bonilla, T.; Mata, R.; Láinez-González, D.; Gonzalo, R.; Castañón, S.; Díaz de la Pinta, F.J.; Blas, C.; López-Lorenzo, J.L.; Alonso-Domínguez, J.M. Spontaneous Remission of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report. Medicina 2024, 60, 807. https://doi.org/10.3390/medicina60050807
Castaño-Bonilla T, Mata R, Láinez-González D, Gonzalo R, Castañón S, Díaz de la Pinta FJ, Blas C, López-Lorenzo JL, Alonso-Domínguez JM. Spontaneous Remission of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report. Medicina. 2024; 60(5):807. https://doi.org/10.3390/medicina60050807
Chicago/Turabian StyleCastaño-Bonilla, Tamara, Raquel Mata, Daniel Láinez-González, Raquel Gonzalo, Susana Castañón, Francisco Javier Díaz de la Pinta, Carlos Blas, José L. López-Lorenzo, and Juan Manuel Alonso-Domínguez. 2024. "Spontaneous Remission of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report" Medicina 60, no. 5: 807. https://doi.org/10.3390/medicina60050807