Necrotic Cell Death Mechanisms and Therapies
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 158
Special Issue Editors
Interests: molecular mechanisms of necrosis; mitochondria; Lysosomes; reactive oxygen species (ROS); calcium signaling; caspase-independent proteases: serine proteases like CELA, as well as Cathepsin C and B, etc.; protease-based drug development against necrosis: siRNAs, small molecules; relevance to diseases
Special Issues, Collections and Topics in MDPI journals
Interests: necrosis; apoptosis; autophagy; proteases; protease inhibitors; elastase; chymotrypsin; cathepsins; myocardial infarction; stroke; cirrhosis
Special Issue Information
Dear Colleagues,
This Special Issue aims to delve into the intricate world of necrotic cell death, exploring its underlying mechanisms and potential therapeutic interventions.
Understanding the intricacies of necrotic cell death mechanisms is imperative for advancing our knowledge of cell biology and developing targeted therapeutic strategies. This Special Issue intends to bring together cutting-edge research and insights from experts in the field, fostering a comprehensive understanding of necrotic cell death pathways.
The importance of this Special Issue lies in its potential to unravel novel therapeutic approaches in order to mitigate pathological conditions associated with necrotic cell death. Additionally, we seek to develop innovative therapies to treat a long line of life-threatening diseases and prolong life.
In summary, this Special Issue will serve as a catalyst for advancing our understanding of necrotic cell death, which emphasizes its relevance in health and disease. The aim is to pave the way for the development of targeted therapies that hold promise for improved patient outcomes in various medical contexts and for life prolongation. In particular, the Special Issue on 'Necrotic Cell Death Mechanisms and Therapies' will explore specific molecular mechanisms and biomolecules that can be targeted to combat necrosis.
Prof. Dr. Ilana Nathan
Dr. Boris Khalfin
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- necrosis
- mitochondria
- lysosomes
- reactive oxygen species (ROS)
- calcium signalling
- caspase-independent proteases: serine proteases like CELA, ELA, as well as cathepsin C and B etc.
- heat shock proteins (HSPs)
- epigenetics
- necrosis in diseases and therapeutic intervention
