Carbon Ion Radiotherapy (Volume II)

Dear Colleagues,

We are excited to invite you to contribute to this Special Issue, which is the second edition of “Carbon Ion Radiotherapy” (https://www.mdpi.com/journal/cancers/special_issues/LO9PF7151E).

Carbon ion radiotherapy is a cancer radiation therapy modality with unique physical and radiobiological properties. The localized dose deposition at the end of the ion range combined with low lateral scattering enables the use of sharp dose gradients for deep-seated tumors. On the other hand, an enhanced therapeutic effect can be achieved due to high ionization density and complex DNA damage. This offers the potential for effective therapy for patients with poor prognoses.

Carbon ion therapy is challenged by the high cost of facilities, increased biological uncertainty and the need for a more exact delivery to realize the dosimetric advantage in clinical reality. While the number of carbon ion therapy facilities remains low, interest in this modality is increasing, and new centers are under construction or at the planning stage, including in the US. Therefore, this Special Issue aims to promote carbon ion radiotherapy and provide an overview of current efforts to prove its biological effectiveness, improve treatment delivery and reduce the cost of treatment.

This Special Issue welcomes submissions on the following topics:

• The efficacy of carbon ion therapy;
• Biological effects and radiobiological modeling;
• Innovative medical accelerators;
• Novel treatment delivery concepts;
• Beam delivery and monitoring improvements;
• Cost optimization.

Dr. Konrad P. Nesteruk
Dr. Christian Graeff
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• carbon ion radiotherapy
• clinical outcome
• radiobiology
• beam delivery
• cost-effectiveness