Diagnosis and Treatment of Cutaneous Melanoma

Dear Colleagues,

Cutaneous melanoma accounts for almost 90% of skin cancer mortality cases. Complete excisional biopsy is mandatory to achieve accurate tumour microstaging that is essential for stratifying the patients’ prognosis and future management, both surgically and with adjuvant medical and immunological therapies. The recent advances in therapeutic options for patients with advanced melanoma have stressed, once again, the importance of accurate staging and early management. In particular, the oncological approach of patients with Stage III disease has changed in recent years. Surgery is recommended less often, and patients may receive potentially life-prolonging systemic therapies. Multidisciplinary discussions on management are recommended, and molecular biology represents an essential tool to integrate the clinico-pathological diagnosis of melanoma.

Dr. Alessandra Filosa
Dr. Francesca Ambrogio
Guest Editors

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• melanoma diagnosis
• molecular pathways
• immunotherapy
• prognostic molecular stratification