Epigenetic Mechanisms Driving Cancer Progression

Dear Colleagues,

This Special Issue research delves into the intricate realm of epigenetics within the context of cancer, aiming to decipher the underlying mechanisms that govern aberrant epigenetic modifications contributing to cancer initiation, progression, and metastasis. The project aims to explore the dynamic interplay between genetic mutations and epigenetic alterations, elucidating how epigenetic modifications regulate gene expression patterns in various cancers. Through comprehensive analyses of DNA methylation, histone modifications, non-coding RNA involvement, and chromatin remodeling, this research endeavors to identify key epigenetic signatures associated with different stages of cancer development.

The Special Issue will focus on employing cutting-edge techniques such as next-generation sequencing, epigenome mapping, and computational biology to unravel the epigenetic landscape in specific cancer types. Furthermore, the study seeks to explore the therapeutic potential of targeting epigenetic modifications as a strategy to reverse or impede cancer progression. Insights gained from this research endeavor aim to contribute substantially to the burgeoning field of epigenetics in oncology, potentially paving the way for novel and more effective targeted therapies tailored towards manipulating epigenetic regulators in cancer cells.

Dr. Yonghwan Shin
Guest Editor

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• cancer
• epigenetic
• next-generation sequencing
• epigenome mapping
• DNA methylation
• histone modifications
• non-coding RNA involvement
• chromatin remodeling