Advancements in Heart Failure Research

Dear Colleagues,

Heart failure persists as a significant global health challenge despite strides in treatment and this Special Issue aims to comprehensively explore recent advancements in heart failure research, from its roots to innovative interventions. understanding the intricate mechanisms driving heart failure is essential to effective management and articles submitted to this Special Issue will delve into pathophysiological processes such as myocardial remodeling, neurohormonal activation, and genetic predispositions. Moreover, this Special Issue seeks to navigate emerging diagnostic modalities such as novel biomarkers, advanced imaging techniques, and artificial intelligence applications, which may prove crucial for timely and accurate diagnosis.

Highlighting the latest therapeutic strategies, from pharmacological interventions to device-based therapies and surgical procedures, this Special Issue underscores precision-medicine approaches, innovative drug therapies, and the role of cardiac devices such as ventricular assist devices and cardiac transplantation. Managing heart failure alongside comorbidities poses unique challenges, addressed in discussions on strategies to tackle common issues such as hypertension, diabetes, and chronic kidney disease. Fostering patient-centered care remains paramount, with a focus on holistic approaches, remote monitoring technologies, and strategies promoting adherence to self-care and treatment.

Lastly, this Special Issue anticipates future trends, examining promising avenues like regenerative medicine and the integration of digital health technologies in personalized care. By bringing together cutting-edge research and insights from leading experts in the field, this Special Issue aims to advance our understanding of heart failure and pave the way toward improved management strategies and patient outcomes.

We invite researchers and clinicians to contribute original research articles, reviews, and perspectives to this Special Issue, with the goal of fostering collaboration and driving innovation in the field of heart failure research.

Prof. Dr. Tzu-Hurng Cheng
Prof. Dr. Ju-Chi Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cardiac remodeling
• biomarkers
• precision medicine
• patient-centered care
• therapeutic innovations

1. Tentative Title: Understanding Galectin-3's Role in Diastolic Dysfunction: A Contemporary Perspective

Auhtors: Wen-Rui Hao, Chun-Yao Cheng, Ju-Chi Liu, Huan-Yuan Chen, Jin-Jer Chen, Tzu-Hurng Cheng