Molecular and Cellular Biology of Human Oncogenic Viruses

Dear Colleagues,

The number of oncovirus-associated cancers has been increasing in recent years; it has been estimated that approximately 10% of neoplastic diseases in the world correlate with viral infections. Therefore, understanding the molecular mechanisms through which oncoviruses regulate viral and host gene expression may help in identifying potential therapeutic targets. There are currently seven recognized viruses associated with human cancer, namely EBV, KSHV, HPV, HTLV-1, HBV, HCV, and MCV. They are able to infect different cell types and can adopt similar and specific strategies to trigger the transformation of their target cells.

The aim of this Special Issue is to provide new insights into the mechanisms underlying viral oncogenesis in the attempt to identify new drugs, enabling the manipulation of the viral lytic cycle, which, in some cases, can be latent or lytic, or target the epigenetic changes and the activation of pro-oncogenic molecular pathways that oncoviruses may induce. The study of mechanisms leading to the establishment of viral infections may also provide useful information on cancer prevention, including the development of vaccines against oncoviruses.

We are looking forward to receiving your contributions.

Dr. Roberta Gonnella
Guest Editor

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• oncoviruses
• antiviral drugs
• viral oncogenesis
• viral infection
• oncogenic pathways
• epigenetics