The Role of Natural Compounds in Cancer Therapy

Dear Colleagues,

A significant number of small-molecule medicines that are used today for the treatment of cancer are natural products or derivatives of natural products. Natural products are bioactive compounds that affect cellular processes including cell metabolism, signaling, and transcription. Advancements in new technologies have been critical in the development of antibody-based therapies. These antibodies bind specific proteins in the cancer cells to affect the activity of specific cancer-causing elements and are also used in targeting specific cancer cells to deliver drugs by designing antibodies with conjugated small molecules.  Chemotherapy using small molecules still remains an approach to treat cancer patients successfully. The mechanisms of the drugs may be altered by natural compounds by affecting cellular processes as well as metabolism, which would affect the outcome of the successful chemotherapy. The natural compounds may also affect the efficacy of the drugs as well as the development of resistance.

This Special Issue invites papers and reviews that add to our knowledge regarding the effects of various natural products on cellular processes and their impact on treatments with current therapies at the molecular level. Submissions can include combination therapies with natural products as well as the repurposing of currently known drugs.

Prof. Dr. Alok Bhushan
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• natural compounds
• cancer
• repurposing
• combination
• polychemotherapy
• pharmaceuticals
• nutraceuticals
• molecular targets
• metabolism
• metabolomics
• enhancing efficacy
• immunotherapy