Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Dental Pulp Stem Cells in Human Disease
edited by Esther Wolfs, Tim Vangansewinkel and
submission deadline 25 May 2024 | 1 articles | Viewed by 419 | Submission Open
Keywords: dental pulp stem cells; disease; regenerative medicine; disease modeling
(This special issue belongs to the Section Stem Cells)
Advances in the Study of Natural Killer (NK) Cells
edited by Fuguo Liu, Mubin Tarannum and Yingjie Zhao
submission deadline 30 May 2024 | 1 articles | Viewed by 3076 | Submission Open
Keywords: natural killer cells; chimeric antigen receptor; immunotherapy; activating receptors; inhibitory receptors
(This special issue belongs to the Section Cellular Immunology)
Melanoma: From Molecular Mechanisms to Therapeutic Opportunities—Series 2 submission deadline 30 May 2024 | 2 articles | Viewed by 1815 | Submission Open
Keywords: melanomagenesis; treatment response; signal transduction; melanoma initiating cells; drug resistance; invasiveness; immune evasion; metastasis; MAPK pathway; PI3K/AKT survival pathways; MEKi; BRAFi; trametinib; dabrafenib; immunotherapies
(This special issue belongs to the Section Cellular Pathology)
Metabolic Regulation of Hematopoietic Stem Cells
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 1223 | Submission Open
Keywords: hematopoietic stem cells; metabolic regulation; mitochondrial function; self-renewal and differentiation; quiescence; energy metabolism; HSC exhaustion; aging; bm niche; leukemia stem cells (LSCs)
(This special issue belongs to the Section Stem Cells)
CRISPR/Cas9-Mediated Gene Therapy in Cancer
edited by , Subhajit Giri and Sharad Awasthi
submission deadline 30 May 2024 | Viewed by 611 | Submission Open
Keywords: CRISPR/Cas; liquid tumor; solid-state cancer; gene therapy; AAV; CAR-T; lipid nanoparticle; immunotherapy; cytotoxicity
(This special issue belongs to the Section Cell Methods)
The Role of Histological Techniques in Neuroscience and Neural Engineering
edited by and Fernando Campos Sánchez
submission deadline 30 May 2024 | Viewed by 189 | Submission Open
Keywords: nerve tissue histology; histochemistry; immunohistochemistry; metal reduction techniques; light & electron microscopy; morphometric analyses; tissue engineering; nerve regeneration; neural degeneration; demyelinating diseases
(This special issue belongs to the Section Tissues and Organs)
Role of Innate Immunity in Chronic Kidney Diseases—Series 2
edited by
submission deadline 30 May 2024 | Viewed by 131 | Submission Open
Keywords: CKD; glomeruli; tubules; sterile inflammation; innate immunity; pattern recognition receptors (PRRs); damage-associated molecular patterns (DAMPs); STING; toll-like receptors; RIG-I; NLRP
(This special issue belongs to the Section Cellular Immunology)
Signaling Pathways in Pregnancy submission deadline 31 May 2024 | 12 articles | Viewed by 24126 | Submission Open
Keywords: cell signaling; proliferation; differentiation; invasion; placentation; placenta; trophoblast; preeclampsia; fetal growth restriction; gestational diabetes mellitus
(This special issue belongs to the Section Cell Signaling)
Advances in Muscle Research in Health and Disease
edited by
submission deadline 31 May 2024 | 5 articles | Viewed by 8484 | Submission Open
Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target
(This special issue belongs to the Section Cell Signaling)
Autophagy and Apoptosis in Skeletal Muscle submission deadline 31 May 2024 | 2 articles | Viewed by 5216 | Submission Open
Keywords: autophagy; apoptosis; skeletal muscle; cell signaling; mitochondria; myopathies; sarcopenia; atrophy; immune system; therapeutic strategies
(This special issue belongs to the Section Autophagy)
Cellular Reprogramming during Sepsis and Potential Therapeutic Targets submission deadline 31 May 2024 | 2 articles | Viewed by 4715 | Submission Open
(This special issue belongs to the Section Cellular Pathology)
Muscle Homeostasis and Regeneration: From Molecular Mechanisms to Therapeutic Opportunities—Series II submission deadline 31 May 2024 | 3 articles | Viewed by 4432 | Submission Open
Keywords: muscle homeostasis; muscle regeneration; satellite cells; stem cells; FAPs; tissue niche; growth factors; inflammatory response; muscle pathology; aging
(This special issue belongs to the Section Cellular Pathology)
Cellular and Molecular Mechanisms Underlying Large-Vessel Vasculitis
edited by and Francesco Muratore
submission deadline 31 May 2024 | 3 articles | Viewed by 4279 | Submission Open
Keywords: large-vessel vasculitis; giant cell arteritis; Takayasu’ s arteritis; Behcet’ s Disease; in vitro/animal models; novel therapy
(This special issue belongs to the Section Cells of the Cardiovascular System)
The Applications of Flow Cytometry: Advances, Challenges, and Trends
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 4227 | Submission Open
Keywords: flow cytometry; single cell; cell function; T-cell subset
(This special issue belongs to the Section Cell Methods)
The Current Applications and Potential of Stem Cell-Derived Organoids submission deadline 31 May 2024 | 2 articles | Viewed by 3282 | Submission Open
Keywords: organoids; stem cell-derived organoids; stem cells; pluripotent stem cells; iPSCs; organ-on-a-chip; disease modelling; cellular therapeutics; regenerative medicine
(This special issue belongs to the Section Stem Cells)
Viruses and Cancer: From Cellular Mechanism to Therapeutic Aspects submission deadline 31 May 2024 | 1 articles | Viewed by 2676 | Submission Open
Keywords: virus-induced cancer; host stress responses; DNA damage response; virus– host interactions; autophagy; cellular innate immunity; cell metabolism; immune evasion mechanisms; inflammation; therapeutic approach
(This special issue belongs to the Section Cell Microenvironment)
Cell Biology: State-of-the-Art and Perspectives in China
edited by Di Chen and
submission deadline 31 May 2024 | 1 articles | Viewed by 2628 | Submission Open
MicroRNA as Biomarker in Carcinoma Cell
edited by , and Eduardo López-Urrutia
submission deadline 31 May 2024 | 1 articles | Viewed by 2427 | Submission Open
Keywords: carcinoma cell; microRNA; prognosis; diagnoses; molecular biomarker; methods for detection; miRNA targets
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Effects of Microglia Changes on Neuroinflammation and Neurodegeneration
edited by Chi-Su Yoon and
submission deadline 31 May 2024 | 1 articles | Viewed by 1800 | Submission Open
Keywords: microglia; neuroinflammation; neurodegenerative disease; neurodegeneration; central nervous system
(This special issue belongs to the Section Cells of the Nervous System)
Regulatory Programs of Skeletal Muscle Repair and Regeneration submission deadline 31 May 2024 | 1 articles | Viewed by 1731 | Submission Open
Research on Proteomics and Its Applications in Disease
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 1666 | Submission Open
Keywords: bottom-up proteomics; top-down proteomics; spatial proteomics; bioinformatics; human diseases; cancer; viral infections; bacterial infections; rare pathologies
(This special issue belongs to the Section Cell Methods)
Highlights in Red Blood Cell Research submission deadline 31 May 2024 | 2 articles | Viewed by 1316 | Submission Open
Keywords: red blood cells; anemia; transfusion; erythropoiesis; signaling
Cancer Stem Cells and Immunotherapy submission deadline 31 May 2024 | Viewed by 637 | Submission Open
Keywords: cancer stem cells; CSC-specific biomarkers; immunotherapies; signaling transduction pathways; tumor microenvironment; metastasis; therapy resistance; DNA repair; cellular metabolism; combination therapies
(This special issue belongs to the Section Cellular Immunology)
Cellular and Molecular Alterations in the Down Syndrome Brain: A Starting Point for the Design of Therapeutic Approaches submission deadline 31 May 2024 | Viewed by 260 | Submission Open
Keywords: down syndrome; cellular defects; deranged molecular pathways; altered neurodevelopment; neurodegeneration; effects of therapies
(This special issue belongs to the Section Cellular Pathology)
Organogenesis and Regeneration: From Basic Research to Medical Study submission deadline 31 May 2024 | Viewed by 243 | Submission Open
Keywords: organogenesis; regeneration; development; proliferation; differentiation; blastema; signaling pathway
(This special issue belongs to the Section Tissues and Organs)
The Role of Apoptosis in Tissue Homeostasis, Malignancies, and Disease Pathogenesis submission deadline 31 May 2024 | Viewed by 237 | Submission Open
Keywords: apoptosis; cell death; p53 pathway; autophagy; caspase; mitochondria; neurodegeneration; inflammation; drug discovery; cancer; targeted anticancer therapy; autoimmunity; nanodelivery
(This special issue belongs to the Section Autophagy)
Mitochondria Meets Oxidative Stress submission deadline 31 May 2024 | Viewed by 229 | Submission Open
Keywords: mitochondria; oxidative stress; reactive oxygen species (ROS); cellular respiration; antioxidant defense; ageing
(This special issue belongs to the Section Mitochondria)
Synapses: Molecular Organization, Regulation and Synaptic Function
edited by Houhui Xia
submission deadline 31 May 2024 | Viewed by 203 | Submission Open
Keywords: synapse; glutamate; GABA; neurotransmitter receptor; scaffolding protein; ion channel; kinase; phosphatase; cell adhesion molecule
(This special issue belongs to the Section Cells of the Nervous System)
Radiation-Induced Brain Injury: Molecular Mechanisms and Therapeutic Strategies
edited by
submission deadline 31 May 2024 | Viewed by 189 | Submission Open
Keywords: radiation injury; brain; neurological and neuropsychiatric disorders; molecular mechanisms; novel therapeutic approaches
(This special issue belongs to the Section Cells of the Nervous System)
Gene Editing in Stem Cells: Next-Generation Stem Cell Therapies
edited by
submission deadline 31 May 2024 | Viewed by 172 | Submission Open
Keywords: gene editing; stem cells; CRISPR/Cas system; ZFN; TALEN
(This special issue belongs to the Section Stem Cells)
Pathophysiological Mechanisms of Cholestatic and Metabolic-Associated Fatty Liver Disease
edited by
submission deadline 31 May 2024 | Viewed by 167 | Submission Open
Keywords: steatosis; steatohepatitis; bile flux; inflammation; FXR
(This special issue belongs to the Section Cellular Pathology)
Pain: Neurobiology, Pathophysiology, and Therapeutic Approaches
edited by Joshua W. Little
submission deadline 31 May 2024 | Viewed by 167 | Submission Open
Keywords: pain; pain pathophysiology; neurobiology; nonopioid therapy; acute pain; chronic pain
(This special issue belongs to the Section Cellular Pathology)
The Signaling and Cellular Mechanisms of Pain—Second Edition
edited by
submission deadline 31 May 2024 | Viewed by 165 | Submission Open
Keywords: nociception; neuropathic pain; visceral pain; pain pathophysiological pathways; glia; analgesia
T-Cell Acute Lymphoblastic Leukaemia submission deadline 31 May 2024 | Viewed by 159 | Submission Open
Keywords: T-cell leukemias; molecular pathogenesis; immune phenotype; T-cell leukemia epidemiology; T-cell ontogeny; transplantation in T-cell leukemia; target therapies
(This special issue belongs to the Section Cellular Immunology)
Role of Hyaluronan in Human Health and Disease
edited by Barbara Triggs-Raine and
submission deadline 31 May 2024 | Viewed by 152 | Submission Open
Keywords: hyaluronan; hyaluronidases; hyaluronan-binding proteins; hyaluronan receptors; fibrosis; cancer; development; immune function
Pathophysiology of Central Nervous System Tumors
edited by Mariëtte E.G. Kranendonk
submission deadline 31 May 2024 | Viewed by 131 | Submission Open
Keywords: CNS tumor; pediatric; adult; molecular profiling; multiomics; microenvironment
(This special issue belongs to the Section Cellular Pathology)
Regulation Mechanisms of Myogenic and Cardiomyogenic Differentiation II
edited by
submission deadline 31 May 2024 | Viewed by 114 | Submission Open
Keywords: stem cells; myogenic differentiation; cardiomyogenic differentiation; regeneration; model systems
Inflammatory Processes in Healthy and Diseased Brains
edited by
submission deadline 1 Jun 2024 | 1 articles | Viewed by 2194 | Submission Open
Keywords: immune response; neurodegeneration; microglia; inflammation; lymphocytes
(This special issue belongs to the Section Cells of the Nervous System)
Metabolic Adaptation Processes in Cancer: Transcriptomic, Proteomic and Metabolomic Studies submission deadline 1 Jun 2024 | Viewed by 320 | Submission Open
Keywords: cancer cell metabolism; inflammation; anticancer drugs; tumor-specific metabolic biomarkers; oxidative stress; omics sciences applied to cancer research; tumor immune microenvironment
(This special issue belongs to the Section Cellular Metabolism)
Gene and Cell Therapy in Regenerative Medicine—Second Edition submission deadline 10 Jun 2024 | 7 articles | Viewed by 9346 | Submission Open
Keywords: gene therapy; cell therapy; regenerative medicine; growth factors; stem cells
(This special issue belongs to the Section Cell and Gene Therapy)
Glioblastoma Cell: From Cellular and Molecular Mechanisms to Innovative Therapy
edited by
submission deadline 10 Jun 2024 | 3 articles | Viewed by 5015 | Submission Open
Keywords: glioblastoma cell line; adjuvant substance; target therapy; molecular pathways; molecular markers; GSCs
(This special issue belongs to the Section Cellular Pathology)
Liver Constituent Cells: Their Niche, Close Intercellular Relationship and Crosstalk with the Extracellular Environment—Current and Future Perspectives (2nd Edition) submission deadline 10 Jun 2024 | Viewed by 115 | Submission Open
Keywords: chronic liver diseases; liver microcirculatory milieu; liver sinusoidal endothelial cells (LSECs); hepatic stellate cells (HSCs); Kupffer cells; hepatocytes; cholangiocytes; sinusoid capillarization; Disse space
(This special issue belongs to the Section Tissues and Organs)
Review Papers in (Re)programming Cells for Cardiac Repair
edited by and
submission deadline 15 Jun 2024 | 4 articles | Viewed by 10723 | Submission Open
Keywords: cardiac programming; cardiogenesis; transcriptional regulation; epigenetics; cardiac tissue engineering
(This special issue belongs to the Section Cells of the Cardiovascular System)
Extracellular Vesicles in Health and Disease 2023 submission deadline 15 Jun 2024 | 5 articles | Viewed by 8168 | Submission Open
Keywords: extracellular vesicles; cancer; cardiovascular diseases; neurodegenerative diseases; autoimmunity and transplantation; innate immunity and inflammation; immunoregulation; infectious diseases
(This special issue belongs to the Section Cellular Pathology)
Hypothalamic Hormonal Secretion and Metabolism
edited by
submission deadline 15 Jun 2024 | 2 articles | Viewed by 4828 | Submission Open
Keywords: hypothalamus; endocrine control; energy homeostasis; hormones; signaling
(This special issue belongs to the Section Cellular Metabolism)
Forkhead-Box (Fox)O Family Transcription Factors in Cancer submission deadline 15 Jun 2024 | 1 articles | Viewed by 1466 | Submission Open
Keywords: forkhead-box class O transcription factors; cancer; apoptosis; tumor progression; EMT; gene transcription; drug resistance; endocrine therapy; lnRNA; PTMs
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Large-Scale Multi-Omic Approaches and Atlas-Based Profiling for Cellular, Molecular, and Functional Specificity, Heterogeneity, and Diversity in the Endocannabinoid System
edited by and
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1155 | Submission Open
Keywords: lipidomics; proteomics; transcriptomics; cluster analysis; massive parallel screening; molecular markers; brain circuits; development; neural plasticity; synapse; appetite and feeding behavior; addiction; pain; epilepsy; neurological disorders
(This special issue belongs to the Section Cells of the Nervous System)
Role of Autophagy in Plant Cells
edited by
submission deadline 15 Jun 2024 | Viewed by 362 | Submission Open
Keywords: autophagy; endoplasmic reticulum; TOR; vacuoles; lysosomes; mitochondria; plastids
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Epigenetics of Brain Function and Diseases submission deadline 15 Jun 2024 | Viewed by 330 | Submission Open
Keywords: neurodevelopmental; neurological; neuropsychiatric; and neurodegenerative disorders; DNA methylation; chromatin remodeling; histone modifications; non-coding RNA; transcriptome; epigenome; epigenetic writers; readers and erasers
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Melanoma and Non-melanoma Skin Cancer: Cellular Mechanisms, Immunity and Therapeutics
edited by
submission deadline 15 Jun 2024 | Viewed by 216 | Submission Open
Keywords: melanoma; squamous cell carcinoma; Merkel cell carcinoma; tumorigenicity; metastasis; therapeutic targets
(This special issue belongs to the Section Cellular Immunology)
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