Latest Review Papers in Medical Microbiology 2024

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 9200

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1. Icona Foundation, 20142 Milan, Italy
2. Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, Department of Health Sciences, University of Milan, 20142 Milan, Italy
Interests: liver diseases; HIV infection; HIV prevention; tuberculosis; clinical infectious diseases; infectious disease epidemiology; mycobacterium tuberculosis; viral infection; immunology of infectious diseases
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Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous special issue "Latest Review Papers in Medical Microbiology 2023".

It aims to collect high-quality review papers in all the fields of medical microbiology. We encourage researchers from related fields to contribute review papers highlighting the latest developments in medical microbiology, or to invite other relevant experts and colleagues to do so. Full length comprehensive reviews will be preferred.

Prof. Dr. Antonella d'Arminio Monforte
Guest Editor

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

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Keywords

  • review papers
  • medical microbiology
  • infectious diseases

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26 pages, 1819 KiB  
Review
MALDI-TOF MS: A Reliable Tool in the Real Life of the Clinical Microbiology Laboratory
by Adriana Calderaro and Carlo Chezzi
Microorganisms 2024, 12(2), 322; https://doi.org/10.3390/microorganisms12020322 - 3 Feb 2024
Cited by 9 | Viewed by 7630
Abstract
Matrix-Assisted Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) in the last decade has revealed itself as a valid support in the workflow in the clinical microbiology laboratory for the identification of bacteria and fungi, demonstrating high reliability and effectiveness in this application. Its [...] Read more.
Matrix-Assisted Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) in the last decade has revealed itself as a valid support in the workflow in the clinical microbiology laboratory for the identification of bacteria and fungi, demonstrating high reliability and effectiveness in this application. Its use has reduced, by 24 h, the time to obtain a microbiological diagnosis compared to conventional biochemical automatic systems. MALDI-TOF MS application to the detection of pathogens directly in clinical samples was proposed but requires a deeper investigation, whereas its application to positive blood cultures for the identification of microorganisms and the detection of antimicrobial resistance are now the most useful applications. Thanks to its rapidity, accuracy, and low price in reagents and consumables, MALDI-TOF MS has also been applied to different fields of clinical microbiology, such as the detection of antibiotic susceptibility/resistance biomarkers, the identification of aminoacidic sequences and the chemical structure of protein terminal groups, and as an emerging method in microbial typing. Some of these applications are waiting for an extensive evaluation before confirming a transfer to the routine. MALDI-TOF MS has not yet been used for the routine identification of parasites; nevertheless, studies have been reported in the last few years on its use in the identification of intestinal protozoa, Plasmodium falciparum, or ectoparasites. Innovative applications of MALDI-TOF MS to viruses’ identification were also reported, seeking further studies before adapting this tool to the virus’s diagnostic. This mini-review is focused on the MALDI-TOF MS application in the real life of the diagnostic microbiology laboratory. Full article
(This article belongs to the Special Issue Latest Review Papers in Medical Microbiology 2024)
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