Recent Advances and Applications of Multiplexed Analysis and Multiplexed Nanobiosensors

Dear Colleagues,

Multiplex analysis has emerged as front-runner technology for the early and reliable diagnosis of diseases through its ability to achieve rapid simultaneous detection of multiple biomarkers, proteins and other clinically significant analytes in a single sample. This approach also enables the collection of more data, a significant reduction in cost, a lower likelihood of errors and a more rapid sample throughput. Recent developments in multiplexing strategies have enabled the clinical diagnosis of some diseases; rapid and reliable simultaneous detection of multiple SARS-CoV-2 mutations; and selective and simultaneous tagging in a single assay of bacteria, cancer cells and individual molecules, such as proteins and DNA. Smartphone-based multiplexed sensors have also emerged as excellent contenders for point-of-care diagnostics.

This Special Issue aims to collect and highlight recent advances in multiplex analysis based on the use of biosensors, nanobiosensors, PCR assays, fluorometric immunoassay, serological assay, CRISPR/Cas multiplexed biosensing, lab-on-chip assay, microfluidic array, lateral flow detection, multiplexed abundance assay, electrochemiluminescent immunoassay, ELISA-based multiplexing, SERS-based multiplex analysis, multiplexed targeted mass spectrometry assay, multiplexed abundance assay and any other related multiplexing methods that have or can be used for the early and reliable diagnosis of diseases or other health conditions, including those utilizing nanomaterials to improve multiple analyte detection. We welcome reviews and research articles in any of these areas.

Prof. Dr. Samuel B. Adeloju
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• multiplex PCR assay, including real-time assay
• multiplex tandem PCR
• fluorometric immunoassay
• multiplex bead-based assay
• electrochemiluminescent immunoassay
• ELISA-based multiplex method
• multiplexed serological assay
• multiplexed targeted mass spectrometry assay
• SERS-based multiplex biomolecular analysis
• CRISPR/Cas multiplexed biosensing
• multiplexed electrohydrodynamic biosensor
• multiple synchronized biosensors
• multiplexed abundance assay
• lab-on-chip assay
• lateral flow detection
• microfluidic array
• SERS tags
• nanomaterial supported and/or enhanced multiplexing