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Research and Application of Platelet-Rich Plasma (PRP)

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 383

Special Issue Editor


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Guest Editor
Division of Oral Bioengineering, Institute of Medicine and Dentistry, Niigata University, Niigata 951-8514, Japan
Interests: platelet concentrates; regenerative dentistry; tissue engineering; quality control
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Since it was first reported in the 1990s, platelet concentrations, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), have been applied in tissue regenerative therapy in various fields. The theoretical basis for use is that concentrated growth factors can be provided by platelet concentrates without serious adverse effects. The advantages of this therapy are its high cost-effectiveness ratio, non-limited commercial availability, and lack of risk of pathogen transfection.

In this Special Issue, we aim to highlight the role of platelets. If non-responders can be detected by monitoring platelet physiological functions and biochemical reactions at molecular levels, this would help realize more predictable PRP therapy. However, the topics of interest are not limited to the aforementioned topics. All in all, in this Special Issue, we explore cutting-edge research on platelet-rich plasma (PRP) and its applications in various biomedical fields. Original, impactful, cutting-edge research and insightful review articles regarding the basic aspects of PRP therapy are highly desirable.

Dr. Tomoyuki Kawase
Guest Editor

Manuscript Submission Information

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Keywords

  • platelet-rich plasma
  • platelet-rich fibrin
  • platelets
  • exosome
  • mitochondria
  • growth factors
  • tissue regeneration

Published Papers (1 paper)

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Review

21 pages, 1521 KiB  
Review
The Biological Role of Platelet Derivatives in Regenerative Aesthetics
by Lorena Cristina Santos, Giselle Lobo Lana, Gabriel Silva Santos, Silvia Beatriz Coutinho Visoni, Rayssa Junqueira Brigagão, Napoliane Santos, Rafaela Sobreiro, Andreza da Cruz Silva Reis, Bruno Lima Rodrigues, Sabrina Ferrari, Claudia Herrera Tambeli and José Fábio Lana
Int. J. Mol. Sci. 2024, 25(11), 5604; https://doi.org/10.3390/ijms25115604 - 21 May 2024
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Abstract
Bioproducts derived from platelets have been extensively used across various medical fields, with a recent notable surge in their application in dermatology and aesthetic procedures. These products, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), play crucial roles in inducing blood vessel [...] Read more.
Bioproducts derived from platelets have been extensively used across various medical fields, with a recent notable surge in their application in dermatology and aesthetic procedures. These products, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), play crucial roles in inducing blood vessel proliferation through growth factors derived from peripheral blood. PRP and PRF, in particular, facilitate fibrin polymerization, creating a robust structure that serves as a reservoir for numerous growth factors. These factors contribute to tissue regeneration by promoting cell proliferation, differentiation, and migration and collagen/elastin production. Aesthetic medicine harnesses these effects for diverse purposes, including hair restoration, scar treatment, striae management, and wound healing. Furthermore, these biological products can act as adjuvants with other treatment modalities, such as laser therapy, radiofrequency, and microneedling. This review synthesizes the existing evidence, offering insights into the applications and benefits of biological products in aesthetic medicine. Full article
(This article belongs to the Special Issue Research and Application of Platelet-Rich Plasma (PRP))
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