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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Studies on Biological Activities of Alkaloids and Their Modifications
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 695
Keywords: alkaloids; chemical modification; biological activity
(This special issue belongs to the Section Biochemistry)
Hepatitis Viruses and Hepatocellular Carcinoma: Research, Treatment and Challenges
edited by
submission deadline 30 May 2024 | Viewed by 646
Keywords: HBV; HDV; HCV; virus replication and pathogenesis; antivirals; virus– cell interaction; vaccine development; hepatocellular carcinoma
(This special issue belongs to the Section Molecular Immunology)
Molecular Docking, Interaction and Mechanism of Action of Bioactive Peptides
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 638
Keywords: bioactive peptides; molecular docking; molecular dynamics simulations; computer-aided screening; structure– activity relationship; bioavailability; bioinformatics
(This special issue belongs to the Section Molecular Informatics)
Health, Disease, and Chronobiology: Molecular and Genetics Aspects submission deadline 30 May 2024 | Viewed by 635
Keywords: chronobiology; timing of food; sleep; time-restricted eating; metabolism; genomics; epigenomics; metabolomics; microbiome; mechanisms
(This special issue belongs to the Section Molecular Biology)
Nanotechnology in the Treatment and Diagnosis of Cancer: Opportunities and Challenges
edited by Lucyna Kapka-Skrzypczak
submission deadline 30 May 2024 | 1 articles | Viewed by 547
Keywords: nanomaterials; cancer; nanomedicine; biological effects; cancer therapy; metastasis
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Mechanism and Treatment of Allergic Asthma
edited by and Marcello Cottini
submission deadline 30 May 2024 | 1 articles | Viewed by 525
Keywords: allergic asthma; epithelial barrier damage; protease allergen; type 2 inflammation
(This special issue belongs to the Section Molecular Immunology)
Advances in Electrochemistry of Metal Nanomaterials
edited by Evangelina Pensa, Miriam C. Rodríguez González and Maria Pilar Carro Reglero
submission deadline 30 May 2024 | Viewed by 510
Keywords: metal nanomaterials; electrochemistry; electrocatalysis; charge storage capabilities; electron transfer kinetics
(This special issue belongs to the Section Molecular Nanoscience)
Drought Stress Tolerance in Plants in 2024
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 509
Keywords: root physiology; drought tolerance; photosynthesis; water deficit stress; shoot– root interaction; salinity; crop plants
(This special issue belongs to the Section Molecular Plant Sciences)
Pathogenetic Factors of Ophthalmological Symptoms in Systemic Diseases submission deadline 30 May 2024 | 1 articles | Viewed by 467
Keywords: diagnosis; uveitis; keratitis; ocular inflammation; hypersensitivity
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Molecular Insights into Antimicrobial Photo-Treatments
edited by Pietro Delcanale
submission deadline 30 May 2024 | 1 articles | Viewed by 418
Keywords: photodynamic inactivation; photo-thermal therapy; photosensitization; antimicrobials; reactive oxygen species; photo-treatments; antibiotic resistance; singlet oxygen; antivirals
(This special issue belongs to the Section Molecular Microbiology)
Crosstalk between Lipids and Immunity
edited by
submission deadline 30 May 2024 | Viewed by 408
Keywords: eicosanoids; sphingolipids; endocannabionoids; specialized pro-resolving mediators; lysophospholipids; lipidomics; membrane-lipids therapy
(This special issue belongs to the Section Molecular Immunology)
Molecular Insight into Dentistry and Craniofacial Surgery: Celebrating the 110th Anniversary of Dentistry in Italy
edited by
submission deadline 30 May 2024 | Viewed by 379
Keywords: dentistry; craniofacial district; technological; oral health; molecular research; materials; restorative dentistry; prosthodontics; oral surgery; implantology; pediatric dentistry; orthodontics; temporomandibular disorder
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Zinc Enzymes for Drug Design and Drug Development submission deadline 30 May 2024 | Viewed by 336
Keywords: zinc enzymes; carbonic anhydrases; matrix metalloproteinases; histone deacetylases; zinc metalloenzymes; drug design
(This special issue belongs to the Section Molecular Pharmacology)
Nanocomposites Based on Graphite and Its Derivatives for Cutting-Edge Applications submission deadline 30 May 2024 | Viewed by 332
Keywords: nanostructures; graphene nanocomposites; sustainable procedures; electrodes; thin films; sensors; photocatalysis; energy conversion; energy storage
(This special issue belongs to the Section Molecular Nanoscience)
Nutrient Sensing in Human Metabolic Diseases: Associated Molecular Mechanisms submission deadline 30 May 2024 | Viewed by 331
Keywords: nutrition; functional food; bioactive compounds; gene; nutrigenomics; nutrigenetics; metabolomics; proteomics; microbiota; chronic diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Immune Modulation of Macrophages 2.0
edited by and Yan Chen
submission deadline 30 May 2024 | Viewed by 323
Keywords: macrophages; treatment; phenotype change; pathway analysis
(This special issue belongs to the Section Molecular Immunology)
RNA-Seq in Human Health and Disease
edited by
submission deadline 30 May 2024 | Viewed by 303
Keywords: aging; bioinformatics; single-cell RNA-Seq; RNA-Seq
(This special issue belongs to the Section Molecular Informatics)
Brain Metastasis 2024
edited by
submission deadline 30 May 2024 | Viewed by 298
Keywords: brain metastasis; brain microenvironment; pathology; circulating tumor cells; tumor-normal cell crosstalks; new biomarkers and therapies for brain metastasis; cerebral spinal fluid/liquid biopsy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Type 2 Diabetes and Its Complications
edited by
submission deadline 30 May 2024 | Viewed by 290
Keywords: diabetes; metabolic defects; β -cell function; dietary intervention; physical exercise
(This special issue belongs to the Section Molecular Biology)
Gene Therapy in Neuropathy
edited by
submission deadline 30 May 2024 | Viewed by 289
Keywords: gene therapy; adeno-associated viral vectors; lentiviral vectors; nanoparticles; antisense oligonucleotides; CRISPR Cas9; RNA; CNS; PNS
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Mechanisms of Musculoskeletal Involvement in Rare Diseases
edited by
submission deadline 30 May 2024 | Viewed by 277
Keywords: rare diseases; molecular pathways; musculoskeletal system; bone involvement; joint degeneration
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Cellular Mechanisms of Gynecologic Malignancies, Benign Diseases 2.0
edited by
submission deadline 30 May 2024 | Viewed by 272
Keywords: gynecologic malignancies; endometrial cancer; ovarian cancer; cervical cancer; uterine cancer; chemotherapy; target therapy; tumor marker; benign gynecologic diseases; endometriosis; polycystic ovary syndrome
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular and Electrophysiological Modulation in Cardiac Arrhythmias
edited by
submission deadline 30 May 2024 | Viewed by 263
Keywords: arrhythmias; cardiac electrophysiology; molecular biology; ion channels; intracellular regulation; intracellular calcium dynamics; trafficking; post-translational modifications; structural alterations; gene expression; animal models; basic; translational and clinical science
(This special issue belongs to the Section Molecular Biology)
Advanced Glycoproteomics Research
edited by
submission deadline 30 May 2024 | Viewed by 262
Keywords: glycosylation; glycoproteomics; site-specific glycan structures; glycan function; biochemical validation
(This special issue belongs to the Section Biochemistry)
Molecular Mechanisms in Dry Eye Disease: Effects on Pathogenesis, Treatment and Ocular Surgery
edited by
submission deadline 30 May 2024 | Viewed by 257
Keywords: dry eye disease; molecular mechanisms pathophysiology; pathogenesis; treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cytokine Signaling in Development, Homeostasis and Disease
edited by
submission deadline 30 May 2024 | Viewed by 254
Keywords: cytokine signaling; development; homeostasis; disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Osteoarthritis Biomarkers, Diagnosis and Treatments
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 253
Keywords: osteoarthritis; degenerative joint disease; biomarkers; diagnosis; treatments
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Primary Cell Line Models in Evolutionary Molecular Physiology
edited by
submission deadline 30 May 2024 | Viewed by 252
Keywords: cell physiology; fibroblasts; comparative biology; evolution; physiological ecology; vertebrates; primary cell line
(This special issue belongs to the Section Molecular Biology)
Plant Bioactive Compounds: Antioxidant, Anti-inflammatory and Anticancer Effects submission deadline 30 May 2024 | Viewed by 224
Keywords: anticancer; antioxidant; anti-inflammatory; bioactive compounds; chemical biology; molecular biology; metabolic diseases; nutrition.
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Role of Steroids and Triterpenoids in Plant Growth, Development and Stress Response 2.0
edited by
submission deadline 30 May 2024 | Viewed by 215
Keywords: biosynthesis; chemical defense; plant growth and development; steroids; sterols; stress response; triterpenoids
(This special issue belongs to the Section Molecular Plant Sciences)
Research Advances in Whole-Genome/Exome Sequencing (WGS/WES) and Next-Generation Sequencing
edited by
submission deadline 30 May 2024 | Viewed by 209
Keywords: short/long-read sequencing; whole-exome sequencing; whole-genome sequencing; bioinformatics; variant classification models; translational medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Dynamics of Redox Metabolism in Plants submission deadline 30 May 2024 | Viewed by 206
Keywords: plant metabolism; plant stress; post-translational modifications; reactive oxygen/nitrogen/sulfur species; redox regulation; signaling
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Advances in Blood–Brain Barrier, Blood–Cerebrospinal Fluid Barrier and Cerebrospinal Fluid–Brain Barriers submission deadline 30 May 2024 | Viewed by 202
Keywords: blood– brain barrier (BBB); blood– cerebrospinal fluid (CSF) barrier (BCSFB); CSF– brain barriers (CSFBB); brain homeostasis; neuroscience; depression; multiple sclerosis; stroke
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural-Derived Nanocarriers as Delivery Systems for Biomolecules
edited by
submission deadline 30 May 2024 | Viewed by 195
Keywords: natural nanocarriers; biomolecules; delivery systems; nanomedicine; human health; controlled release
(This special issue belongs to the Section Molecular Biology)
Model Organisms in Plant Science: Metal Transport in Tomato
edited by
submission deadline 30 May 2024 | Viewed by 186
Keywords: metal; uptake; translocation; sequestration; transmembrane transport
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Computational Modelling in the Context of Safe and Sustainability-by-Design Strategy
edited by Alicja Mikołajczyk
submission deadline 30 May 2024 | Viewed by 184
Keywords: molecular informatics; molecular computational modelling; materials modeling; molecular study; chemoinformatic design
(This special issue belongs to the Section Molecular Informatics)
Advances in Molecular Research of Diabetic Cardiomyopathy submission deadline 30 May 2024 | Viewed by 180
Keywords: diabetic cardiomyopathy; apoptosis; diabetes; myocardial fibrosis; stem cells; inflammation; therapeutic approaches
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Circadian Biology in Human Health and Disease
edited by Flore Sinturel
submission deadline 30 May 2024 | Viewed by 180
Keywords: circadian rhythms; metabolism; misalignment; synchronization; molecular clock; internal body clocks; sleep– wake cycle
(This special issue belongs to the Section Molecular Biology)
Editorial Board Members’ Collection Series: Chemical Molecular Structure, Function and Reactions submission deadline 30 May 2024 | Viewed by 176
Keywords: chemical molecules; chemical reactions; molecules interations; molecules structure; molecular dynamics
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Bioactive Materials with Antimicrobial Properties 2.0 submission deadline 30 May 2024 | Viewed by 174
Keywords: bioactivity; biomedical application; smart packaging; aerospace; textile; antimicrobic activity; antifungal activity
(This special issue belongs to the Section Molecular Microbiology)
The Powerhouse: Mitochondria in Health and Disease
edited by
submission deadline 30 May 2024 | Viewed by 173
Keywords: mitochondria; targeted therapies; metabolism; ROS; bioenergetics; disease
(This special issue belongs to the Section Molecular Biology)
Advances in the Research of Alzheimer’s Disease and Dietary Neuroprotective Agents submission deadline 30 May 2024 | Viewed by 169
Keywords: neurodegenerative disorders; brain health; brain– gut-microbiome axis; blood– brain barrier assays; anti-inflammatory activity; antichlolinergic activity; antioxidant activity; bioactive phytochemicals; mechanisms of neuroprotection; brain foods; neuroprotection
(This special issue belongs to the Section Molecular Neurobiology)
Drug Resistance Mechanisms in Human Cancer Cells to Anticancer Drugs
edited by
submission deadline 30 May 2024 | Viewed by 151
Keywords: cancer therapy; targeted therapy; combination therapy; drug resistance; resensitization; DNA repair; DNA damage response; DNA repair inhibitors; synthetic lethality; chemoradiation
(This special issue belongs to the Section Molecular Pharmacology)
Mechanistic Studies of Mitosis
edited by Eleni Petsalaki
submission deadline 30 May 2024 | Viewed by 151
Keywords: mitosis; cancer; cell biology; spindle checkpoint; abscission; abscission checkpoint; cytokinesis
(This special issue belongs to the Section Biochemistry)
Advanced Research on Obesity and Cancer
edited by
submission deadline 30 May 2024 | Viewed by 150
Keywords: obesity; body fat; cancer; adipokines; leptin; adiponectin; angiogenesis; molecular activity; signaling pathways
(This special issue belongs to the Section Molecular Oncology)
Molecular Mechanisms and Therapeutic Advances in Brain Metastasis
edited by Malcolm Lim
submission deadline 30 May 2024 | Viewed by 146
Keywords: brain metastasis; brain microenvironment; neurotransmitters co-option; blood-tumour barrier; cancer drug delivery; targeted radiotherapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Anti-hypoxia and Oxygenation Agents for Cancer Immunotherapy
edited by Stephen M. Hatfield and Bruce D. Spiess
submission deadline 30 May 2024 | Viewed by 135
Keywords: oxygenation agents; blood substitutes; immune checkpoint inhibitors; cancer immunotherapies; target tumor hypoxia; hypoxia-targeting prodrugs; perfluorocarbons; injectable oxygen microparticles
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms of Primary Graft Dysfunction and Acute Rejection in Solid Organ Transplantation
edited by
submission deadline 30 May 2024 | Viewed by 134
Keywords: transplant; graft dysfunction; ischemia– reperfusion injury; DAMPs; immune cells; allo-antigens; acute rejection; metabolism; cell death; MHC; PRRs
(This special issue belongs to the Section Molecular Immunology)
Molecular Research on Pharmacogenetics
edited by Stefania Cheli
submission deadline 30 May 2024 | Viewed by 115
Keywords: pharmacogenetics; pharmacokinetics; pharmacodynamics; genotype; haplotype; biomarker; single-nucleotide polymorphism; genomic variant; genetic testing; adverse drug reactions; clinical implementation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Research on Vitamin D Metabolism in Disease
edited by Arnaud Molin
submission deadline 30 May 2024 | Viewed by 111
Keywords: vitamin D; vitamin D receptor; vitamin D metabolizing enzyme; vitamin D metabolism; vitamin D regulation; calcium– phosphate homeostasis; cell differenciation; cell proliferation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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