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Active Ingredients in Functional Foods and Their Impact on Health

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 30 November 2024 | Viewed by 137

Special Issue Editor


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Guest Editor
Department of Bromatology, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Mickiewicza 2D Street, 15-222 Białystok, Poland
Interests: dietary supplements; pharmacy; food quality assessment; nutrition assessment
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the exploration of active ingredients in functional foods and their impact on health has emerged as a dynamic and critical area of research. This interdisciplinary field delves into the bioactive components of various foods, ranging from traditional staples to modern dietary innovations, with a focus on elucidating their physiological effects and potential health benefits.

Researchers in this domain investigate the multifaceted roles of active ingredients, such as polyphenols, flavonoids, omega-3 fatty acids, probiotics, and other bioactive compounds found in foods. The study encompasses their mechanisms of action, bioavailability, and the intricate interplay between these components and the human body.

The health implications of these active ingredients are diverse, spanning preventive and therapeutic aspects. Studies explore their anti-inflammatory, antioxidant, antimicrobial, and immune-modulating properties, offering potential avenues for combating chronic diseases, enhancing overall well-being, and supporting personalized nutrition approaches.

This Special Issue aims to gather cutting-edge research that unravels the complexities of active ingredients in functional foods. It welcomes contributions elucidating the molecular mechanisms behind their health effects, innovative methods for extraction and analysis, and clinical studies validating their therapeutic potentials. Furthermore, the interrelation between dietary patterns, active ingredients, and health outcomes is a key area of interest.

Researchers and practitioners from various disciplines, including food chemistry, pharmacology, and medicine, are invited to contribute their insights, fostering a comprehensive understanding of how active ingredients in functional foods can positively impact human health.

Dr. Anna Puścion-Jakubik
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • functional foods
  • active ingredients
  • bioactive compounds
  • health impact
  • nutraceuticals
  • dietary patterns
  • personalized nutrition

Published Papers (1 paper)

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Research

15 pages, 5444 KiB  
Article
Investigating the Hepatoprotective Properties of Mulberry Leaf Flavonoids against Oxidative Stress in HepG2 Cells
by Qinhua Zheng, Ke Feng, Wenting Zhong, Weijian Tan, Sa Rengaowa and Wenzhong Hu
Molecules 2024, 29(11), 2597; https://doi.org/10.3390/molecules29112597 (registering DOI) - 31 May 2024
Abstract
Abstract: Oxidative stress significantly contributes to ageing and disease, with antioxidants holding promise in mitigating its effects. Functional foods rich in flavonoids offer a potential strategy to mitigate oxidative damage by free radicals. We investigated the protective effects of mulberry leaf flavonoids (MLF) [...] Read more.
Abstract: Oxidative stress significantly contributes to ageing and disease, with antioxidants holding promise in mitigating its effects. Functional foods rich in flavonoids offer a potential strategy to mitigate oxidative damage by free radicals. We investigated the protective effects of mulberry leaf flavonoids (MLF) against H2O2-induced oxidative damage in HepG2 cells. It assessed the inhibitory effect of MLF (62.5-500 μg/mL) on H2O2-induced oxidative damage by analyzing cellular morphology and oxidative stress markers, including ROS production, mitochondrial membrane potential, antioxidant enzyme levels, MDA, and apoptosis-related proteins. The results demonstrated that MLF prevented spiny cell formation triggered by 750 μM H2O2 and significantly reduced ROS levels, restored mitochondrial membrane potential, decreased lactate dehydrogenase and alanine transaminase leakage, and reduced MDA content induced by H2O2. MLF also modulated antioxidant enzymes and attenuated oxidative damage to HepG2 cell DNA, as confirmed by staining techniques. These findings indicate the potential of MLF as a hepatoprotective agent against oxidative damage in HepG2 cells. Full article
(This article belongs to the Special Issue Active Ingredients in Functional Foods and Their Impact on Health)
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