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Nutrients
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Effects of Dietary Fatty Acid on Obesity
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Effects of Dietary Fatty Acid on Obesity

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".

Deadline for manuscript submissions: closed (25 March 2024) | Viewed by 519

Special Issue Editor

Prof. Dr. Masao Yamasaki

E-Mail Website
Guest Editor
Graduate School of Agriculture, University of Miyazaki, 1-1 Gakuen Kibanadai-Nishi, Miyazaki 889-2192, Japan
Interests: lipids; plant extracts; obesity; lifestyle disease; cancer; apoptosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

There is a close relationship between dietary fat and our body shape, and it is becoming increasingly clear that the composition of dietary fatty acids and the intake of certain functional fatty acids have an impact on obesity and metabolic disorders. In understanding the functions of fatty acids, it is important to clarify their metabolic changes and interactions with biological molecules, and preliminarily, information obtained through comprehensive analysis by metabolomics and lipidomics can also contribute greatly to future research progress. This Special Issue of Nutrients entitled “Effects of Dietary Fatty Acid on Obesity” welcomes original research including preliminary studies and reviews of the literature concerning this important topic.

Prof. Dr. Masao Yamasaki
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fatty acids
  • metabolic disorders
  • obesity
  • metabolome

Published Papers (1 paper)

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Research

12 pages, 2958 KiB  
Article
Daily Consumption of α-Linolenic Acid Increases Conversion Efficiency to Eicosapentaenoic Acid in Mice
by Saori Watabe, Wataru Tanaka, Hiroyuki Sakakibara and Daigo Yokoyama
Nutrients 2024, 16(10), 1407; https://doi.org/10.3390/nu16101407 - 7 May 2024
Viewed by 306
Abstract
To maintain a beneficial concentration of eicosapentaenoic acid (EPA), the efficient conversion of its precursor, α-linolenic acid (α-LA), is important. Here, we studied the conversion of α-LA to EPA using ICR and C57BL/6 mice. A single dose of perilla oil rich-in α-LA or [...] Read more.
To maintain a beneficial concentration of eicosapentaenoic acid (EPA), the efficient conversion of its precursor, α-linolenic acid (α-LA), is important. Here, we studied the conversion of α-LA to EPA using ICR and C57BL/6 mice. A single dose of perilla oil rich-in α-LA or free α-LA had not been converted to EPA 18 h following administration. The α-LA was absorbed into the circulation, and its concentration peaked 6 h after administration, after which it rapidly decreased. In contrast, EPA administration was followed by an increase in circulating EPA concentration, but this did not decrease between 6 and 18 h, indicating that the clearance of EPA is slower than that of α-LA. After ≥1 week perilla oil intake, the circulating EPA concentration was >20 times higher than that of the control group which consumed olive oil, indicating that daily consumption, but not a single dose, of α-LA-rich oil might help preserve the physiologic EPA concentration. The consumption of high concentrations of perilla oil for 4 weeks also increased the hepatic expression of Elovl5, which is involved in fatty acid elongation; however, further studies are needed to characterize the relationship between the expression of this gene and the conversion of α-LA to EPA. Full article
(This article belongs to the Special Issue Effects of Dietary Fatty Acid on Obesity)
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