Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Topoisomerases as Targets for Novel Drug Discovery
edited by
submission deadline 30 May 2024 | 7 articles | Viewed by 16909 | Submission Open
Keywords: topoisomerase; type I topoisomerase; type II topoisomerase; DNA Gyrase; DNA topology; catalytic inhibitors; topo II poisons; DNA gyrase inhibitors; Novel bacterial topoisomerase inhibitors (NBTI); anticancer agents; antibacterial agents
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Nuclear Factor Kappa-B (NF-kB) Inhibitors for Cancer Therapy
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 5446 | Submission Open
Keywords: NF-kB inhibitors; natural compounds; metabolism reprogramming; immunomodulation; combination treatments; treatment resistance
(This special issue belongs to the Section Medicinal Chemistry)
New Advances in Mesenchymal Stromal Cells as Therapeutic Tools submission deadline 31 May 2024 | 10 articles | Viewed by 20717 | Submission Open
Keywords: mesenchymal stromal cells; cell therapy; immunomodulation; regeneration; regenerative medicine; bioprocessing; bioengineering; inflammatory diseases; degenerative diseases
(This special issue belongs to the Section Biopharmaceuticals)
Pharmacokinetics and Pharmacodynamics of Psychoactive Substances: Clinical and Forensic Aspects 2023 submission deadline 31 May 2024 | 1 articles | Viewed by 2052 | Submission Open
Keywords: psychoactive substances; toxicokinetics; toxicodynamics; toxicological analysis; interpretation of toxicological reports; antemortem toxicology; postmortem toxicology; clinical and forensic issues
(This special issue belongs to the Section Pharmacology)
Application of 2D and 3D-QSAR Models in Drug Design
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 1700 | Submission Open
Keywords: 2D-QSAR; 3D-QSAR; Hansch analysis; Free– Wilson; structure-activity relationships; CoMFA; CoMSIA; drug design; molecular docking; molecular dynamics.
(This special issue belongs to the Section Medicinal Chemistry)
Therapeutic Targets and Therapies in Graft versus Host Disease (GVHD) submission deadline 31 May 2024 | 1 articles | Viewed by 1178 | Submission Open
Keywords: malignant disorders; hematopoietic cell transplantation; graft-versus-host disease (GVHD); therapeutic targets; bone marrow transplant; stem cell transplant
(This special issue belongs to the Section Pharmacology)
Pharmacology and Toxicology of Opioids
edited by , Joana Barbosa and
submission deadline 31 May 2024 | Viewed by 735 | Submission Open
Keywords: opioid toxicity; opioid pharmacodynamics; opioid pharmacokinetics; opioid pharmacogenetics; prescription opioids; toxicity assays; in vivo; in vitro; abuse; dependence
(This special issue belongs to the Section Pharmacology)
Cell Fate Manipulation for Bone and Cartilage Reconstruction
edited by and Qian Wang
submission deadline 31 May 2024 | Viewed by 289 | Submission Open
Keywords: bone and cartilage reconstruction; cell fate; biophysical cues; biochemical cues; stem cells; extracellular vesicles
(This special issue belongs to the Section Biopharmaceuticals)
Structure and Ligand Based Drug Design
edited by
submission deadline 10 Jun 2024 | 9 articles | Viewed by 22064 | Submission Open
(This special issue belongs to the Section Medicinal Chemistry)
Natural Terpenoids as Drug Candidates
edited by and
submission deadline 10 Jun 2024 | Viewed by 277 | Submission Open
(This special issue belongs to the Section Natural Products)
Recent Advances in Antimicrobial Nano-Drug Delivery Systems submission deadline 15 Jun 2024 | Viewed by 150 | Submission Open
Keywords: infectious diseases; antimicrobial resistance; antibiotics; antifungal drugs; nanostructures; pathogen adaptation; nanomedicine
(This special issue belongs to the Section Pharmaceutical Technology)
Pharmacotherapy of Neuropathic Pain submission deadline 20 Jun 2024 | 9 articles | Viewed by 18501 | Submission Open
Keywords: neuropathy; nerve damage; somatosensory system; pharmacology; natural products; lipid mediators; biologicals; anticonvulsants; cannabinoids
(This special issue belongs to the Section Pharmacology)
Next-Generation Contrast Agents for Medical Imaging
edited by and
submission deadline 20 Jun 2024 | 9 articles | Viewed by 14455 | Submission Open
Keywords: targeting; contrast agent; medical imaging; radiolabeling; paramagnetic; magnetic resonance imaging; positron emission tomography; optical imaging; SPECT; X-ray
The 20th Anniversary of Pharmaceuticals—How Artificial Intelligence Is Reshaping Pharmaceuticals Technology
edited by
submission deadline 20 Jun 2024 | 5 articles | Viewed by 7502 | Submission Open
Keywords: drug delivery; drug analysis; pharmaceutical technology; controlled release and sustained release; formula design; artificial intelligence
(This special issue belongs to the Section Pharmaceutical Technology)
Exploring Natural Metabolites to Identify Novel Potential Therapeutic Agents submission deadline 20 Jun 2024 | 4 articles | Viewed by 6855 | Submission Open
Keywords: hit identification; marine microorganisms; computational approaches; in vivo/in vitro assays; active metabolites; fungi; drug discovery; natural products; functional foods
(This special issue belongs to the Section Natural Products)
Osteogenesis Imperfecta—Current and Future Therapies submission deadline 20 Jun 2024 | 3 articles | Viewed by 4586 | Submission Open
Keywords: osteogenesis imperfecta (OI); ; antiresorptive therapy (bisphosphonates; denosumab); ; bone anabolic agents (teriparatide and inhibitors of sclerostin and TGF-β ); ; inductors of autophagy (4-PBA; natural products); ; new approaches for OI treatment
(This special issue belongs to the Section Natural Products)
Advanced Strategies in Drug Design and Development of Small Molecules as Therapeutic Agents
edited by
submission deadline 20 Jun 2024 | 4 articles | Viewed by 4019 | Submission Open
(This special issue belongs to the Section Medicinal Chemistry)
New Approaches for the Prevention and Alleviation of Metabolic Syndrome 2024
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1157 | Submission Open
Keywords: metabolic disorder; IBD; diabetes; hypertension; obesity
(This special issue belongs to the Section Pharmacology)
Design, Synthesis, and Evaluation of Nucleobase, Nucleoside, and Nucleotide Analogues
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1147 | Submission Open
Keywords: nucleobase; nucleoside; nucleotide; drug design; structural mimicry; enzyme inhibitors; anticancer agents; antivirals
(This special issue belongs to the Section Biopharmaceuticals)
Sirtuins as Novel Biological Targets for Pharmacological Intervention in Physiology and Pathology submission deadline 20 Jun 2024 | Viewed by 802 | Submission Open
Keywords: sirtuins; metabolism; cancer; hypoxia; damage recovery; cell death
(This special issue belongs to the Section Pharmacology)
Data-Driven Biomarker and Drug Discovery for Complex Disease
edited by , Tao Ban and
submission deadline 20 Jun 2024 | 1 articles | Viewed by 593 | Submission Open
Keywords: cardiovascular disease; diabetes; neurodegenerative diseases; genomics; proteomics; metabolomics; systems biology; data mining; biomarker; drug discovery
(This special issue belongs to the Section Pharmacology)
Application of Membrane Transporters in Drug Development
edited by and
submission deadline 20 Jun 2024 | Viewed by 555 | Submission Open
Keywords: membrane transporters; ABC; SLC; transporter-mediated drug; drug– drug interaction; drug development; pharmacological barriers
(This special issue belongs to the Section Pharmaceutical Technology)
Phage Discovery and Phage Therapy
edited by Sha Liu and Nan Hao
submission deadline 20 Jun 2024 | Viewed by 465 | Submission Open
Keywords: phage discovery; phage biology; phage engineering; phage lysins; phage therapy
(This special issue belongs to the Section Biopharmaceuticals)
Therapeutics for Ferroptosis in CNS Disease
edited by
submission deadline 20 Jun 2024 | Viewed by 309 | Submission Open
Keywords: iron; free radicals; oxidative stress; neurodegeneration; hypoxia; antioxidants; iron chelators; ABC transporters
(This special issue belongs to the Section Pharmacology)
Antimicrobial Peptides: Design, Synthesis and Pharmaceutical Applications
edited by
submission deadline 20 Jun 2024 | Viewed by 144 | Submission Open
Keywords: natural antimicrobial peptides; antimicrobial peptide design and modifications; antimicrobial peptide structures; antimicrobial peptide stability; mechanism/mode of action of antimicrobial peptides; antimicrobial peptide applications; modulation of infection-related immune and inflammation by peptides; extended applications of antimicrobial peptides for treatments of cancers and other diseases; clinical trials of pharmaceutical peptides
(This special issue belongs to the Section Biopharmaceuticals)
Choline Kinase as a Therapeutic Target
edited by Tahl Zimmerman and
submission deadline 20 Jun 2024 | Viewed by 122 | Submission Open
Keywords: choline kinase; inhibitors; antitumor; antiparasitic; antibiotics; immunotherapy
(This special issue belongs to the Section Medicinal Chemistry)
New Insights into Therapy for Alzheimer’s and Other Neurodegenerative Diseases
edited by Robert Joseph Shmookler Reis, Meenakshisundaram Balasubramaniam and
submission deadline 22 Jun 2024 | 3 articles | Viewed by 10439 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; amyotrophic lateral sclerosis; neurodegeneration; inflammation; anti-inflammatory drugs; post-translational modifications; protein misfolding; protein aggregation
(This special issue belongs to the Section Pharmacology)
Current Therapies for Endometriosis, Adenomyosis and Endometrial Cancer
edited by Ambrogio Pietro Londero, and
submission deadline 22 Jun 2024 | 3 articles | Viewed by 6385 | Submission Open
Keywords: endometriosis; adenomyosis; endometrial cancer; hormonal therapy; non-hormonal therapy; pain management; fertility preservation; complementary/alternative medicine; radiation therapy; chemotherapy; immunotherapy
(This special issue belongs to the Section Pharmacology)
Design, Synthesis and Biological Evaluation with Potential Anti-inflammatory Activity submission deadline 22 Jun 2024 | 2 articles | Viewed by 3234 | Submission Open
Keywords: anti-inflammatory; COX/LOX; IL-6; JAK; STAT3; p38MAPK; TNF-α ; asthma; Alzheimer's disease; cancer
(This special issue belongs to the Section Medicinal Chemistry)
Long Noncoding RNAs as Pharmacological Targets in Neurological Diseases submission deadline 22 Jun 2024 | 2 articles | Viewed by 2625 | Submission Open
Keywords: LncRNAs; neurodevelopment; neurodegeneration; epigenetics; non-coding RNAs; gene therapy
(This special issue belongs to the Section Pharmacology)
Natural Products Derived from Fungi and Their Biological Activities
edited by
submission deadline 23 Jun 2024 | Viewed by 216 | Submission Open
Keywords: fungi; medicinal fungi; fruiting bodies; mycelial cultures; bioactive compounds; pro-health activity; mushroom products; natural therapy; natural medicines
(This special issue belongs to the Section Natural Products)
HIV and Viral Hepatitis: Prevention, Treatment and Coinfection submission deadline 24 Jun 2024 | 1 articles | Viewed by 1912 | Submission Open
Keywords: coinfection; drug discovery; HBV; HCV; HDV; HIV; neutralizing antibodies; prevention; treatment; vaccine
(This special issue belongs to the Section Biopharmaceuticals)
Drug-Induced and Herbal Hepatotoxicity and Methods of Its Prevention submission deadline 25 Jun 2024 | 6 articles | Viewed by 18536 | Submission Open
Keywords: drug-induced hepatotoxicity; herbal hepatotoxicity; acute and chronic liver damage; pathomechanisms of liver injury; oxidative stress; inflammation; apoptosis and necrosis; fibrosis
(This special issue belongs to the Section Pharmacology)
Pharmacological Treatments for Melanoma submission deadline 25 Jun 2024 | 7 articles | Viewed by 11321 | Submission Open
Keywords: advanced melanoma; immune escape; metastasis; targeted therapies; biomarkers; precision medicine; tumor microenvironment
(This special issue belongs to the Section Pharmacology)
Drug Candidates for the Treatment of Oral Cancer and Oral Cancer Pain
edited by
submission deadline 25 Jun 2024 | 6 articles | Viewed by 11318 | Submission Open
Keywords: oral cancer; oral cancer pain; drug discovery; natural compounds; immunotherapy; small molecule inhibitors; biomarkers
(This special issue belongs to the Section Medicinal Chemistry)
Photodynamic Therapy 2023
edited by
submission deadline 25 Jun 2024 | 7 articles | Viewed by 8627 | Submission Open
Keywords: photodynamic therapy; photosensitizers; nanoparticles; photodiagnosis; targeting; antimicrobial; X-rays excitation; two photon and upconversion; immunomodulation; dosimetry; hypoxia
(This special issue belongs to the Section Pharmaceutical Technology)
Botanicals: Bioactive Molecules and Therapeutic Properties for Human Health 2023 submission deadline 25 Jun 2024 | 4 articles | Viewed by 7733 | Submission Open
Keywords: isolation/characterization of plant metabolites; biosynthesis of medicinal botanicals; chemical synthesis of botanicals; biological activity screening of botanicals; medicinal chemistry evaluation of botanicals; application of computational methods to study bioactive botanicals; phytochemical-derived drug leads
(This special issue belongs to the Section Natural Products)
Network Pharmacology of Natural Products submission deadline 25 Jun 2024 | 3 articles | Viewed by 6424 | Submission Open
Keywords: natural compounds; plant extracts; structure-activity relationship; network pharmacology; multitarget effects; synergy of complex preparations; pleiotropic activity
(This special issue belongs to the Section Natural Products)
Polyphenols in the Treatment for Neuroinflammation-Induced Neurodegenerative Disease submission deadline 25 Jun 2024 | 3 articles | Viewed by 6031 | Submission Open
(This special issue belongs to the Section Natural Products)
Pyrazole and Thiazole Derivatives in Medicinal Chemistry submission deadline 25 Jun 2024 | 3 articles | Viewed by 3942 | Submission Open
(This special issue belongs to the Section Medicinal Chemistry)
Drug Analysis and Therapeutic Drug Monitoring
edited by , Ana Catalán Latorre and
submission deadline 25 Jun 2024 | 4 articles | Viewed by 3892 | Submission Open
Keywords: personalized medicine; therapeutic drug monitoring; pharmacokinetics model; pharmacometric model; drug bioanalysis; clinical pharmaceutics
(This special issue belongs to the Section Pharmacology)
Toxicological Effects of Drug Abuse and Its Consequences on Health submission deadline 25 Jun 2024 | 2 articles | Viewed by 3658 | Submission Open
Keywords: addiction; drug abuse; toxicology; treatment; bioactive compound
(This special issue belongs to the Section Pharmacology)
Combining Immunotherapy and Targeted Therapies in Cancer Treatment
edited by , and Marek Ziobro
submission deadline 25 Jun 2024 | 2 articles | Viewed by 3401 | Submission Open
Keywords: immunotherapy; PDL/PDL1
(This special issue belongs to the Section Pharmacology)
Therapeutic Agents for the Treatment of Tumors in the CNS submission deadline 25 Jun 2024 | 1 articles | Viewed by 3373 | Submission Open
Keywords: primary brain tumors; glioblastoma; brain metastases (BMs); neuro-oncology; blood– brain barrier (BBB); drug delivery; preclinical PK/PD; molecularly targeted agents; immunotherapy; new modalities
Hydrogels for Pharmaceutical and Biomedical Applications 2024 submission deadline 25 Jun 2024 | 3 articles | Viewed by 2798 | Submission Open
Keywords: hydrogel; pharmaceutical applications; biomedical applications; drug delivery system; tissue engineering
(This special issue belongs to the Section Pharmaceutical Technology)
Design and Synthesis of Small Molecule Kinase Inhibitors submission deadline 25 Jun 2024 | 2 articles | Viewed by 2219 | Submission Open
Keywords: protein kinases; cancer; small molecule kinase inhibitors; heterocyclic compounds; cancer resistance; targeted therapy; cancer-altered pathway; genetic mutations; FDA-approved kinase inhibitors; kinase inhibitors combinations
(This special issue belongs to the Section Medicinal Chemistry)
Novel Anti-proliferative Agents 2024
edited by
submission deadline 25 Jun 2024 | 2 articles | Viewed by 2046 | Submission Open
Keywords: medicinal chemistry; drug discovery; natural compounds; synthetic compounds; organic synthesis; bioactivity; anticancer drugs; antiproliferative activity
(This special issue belongs to the Section Medicinal Chemistry)
The 20th Anniversary of Pharmaceuticals—Metal-Based Drugs for Cancer Treatment, Antibacterial and Antiviral Applications submission deadline 25 Jun 2024 | 1 articles | Viewed by 1628 | Submission Open
Keywords: metal-based drugs; anticancer compounds; antivirals; antibiotics; chemotherapy; drug targeting; delivery strategies; drug repurposing; medicinal chemistry; bioinorganic chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Drug-Drug Interactions (DDI) and Personalized Medicine in Oncology
edited by and Andrea Botticelli
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1493 | Submission Open
(This special issue belongs to the Section Pharmacology)
Small Molecules in Cancer Immunotherapy submission deadline 25 Jun 2024 | 1 articles | Viewed by 1484 | Submission Open
Keywords: cancer immunotherapy; small molecules; immunocheckpoints; PD-1/PD-L1; A2A/A2B adenosine receptors; toll-like receptor; chemokine receptors; CD39/CD73
(This special issue belongs to the Section Medicinal Chemistry)
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