COVID-19 Complications and Co-infections

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Coronaviruses".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 546

Special Issue Editors


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Guest Editor
School of Medicine, University of New Mexico, Albuquerque, NM, USA
Interests: COVID-19 complications; clinical outcomes with COVID-19 disease; systemic disorders

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Guest Editor
West Penn Allegheny Health System, Pittsburgh, PA, USA
Interests: COVID-19; acute respiratory distress syndrome; asthma and COPD

Special Issue Information

Dear Colleagues,

Since the outbreak of the COVID-19 pandemic in 2019, our understanding of the disease has undergone rapid development. We have gained significant insights into COVID-19, including its risk factors, pathophysiology, clinical course, outcomes, complications, prognosis, associated co-morbid conditions and co-infections, as well as optimal treatment and management options. However, despite these advancements, there are still notable gaps in our knowledge, especially as new variants continue to evolve.

This Special Issue examines the short- and long-term clinical outcomes of COVID-19 disease and its associated co-infections. We especially welcome:

  1. Virology research that presents original empirical studies (using qualitative, mixed, and quantitative methods), systematic reviews, short communications, case reports, and brief reports that contribute to our understanding of the course, outcomes, and prognosis of COVID-19;
  2. Respiratory system complications associated with COVID-19 that include cardiovascular disease, thrombosis, kidney damage, neurological conditions, and gastrointestinal symptoms. These complications, together with co-infections such as bacterial pneumonia, influenza virus infection, and fungal infections, can increase the severity and complexity of the disease;
  3. Critical perspectives and articles that examine how clinical and public health initiatives and interventions can effectively reduce morbidity, mortality, and the burden on healthcare systems caused by COVID-19, which are crucial. Understanding the nature of these complications and co-infections is important for informing strategies to effectively manage and treat COVID-19.

We aim to bridge existing knowledge gaps and advance our understanding of COVID-19 and its associated co-infections and complications. Global perspectives in submissions are welcomed.

Dr. Amir Sohail
Dr. Abu Baker Sheikh
Dr. Adeel Nasrullah
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • SARS-CoV-2
  • COVID-19
  • complications
  • co-infections
  • hospitalization

Published Papers (1 paper)

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Research

12 pages, 1604 KiB  
Article
The Impact of COVID-19 during Pregnancy on Maternal Hemodynamic Function, Angiogenic Markers and Neonatal Outcome
by Nawa Schirwani-Hartl, Lena Tschanun, Pilar Palmrich, Christina Haberl, Nicole Perkmann-Nagele, Herbert Kiss, Angelika Berger and Julia Binder
Viruses 2024, 16(6), 868; https://doi.org/10.3390/v16060868 - 29 May 2024
Viewed by 205
Abstract
Infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) in pregnancy are associated with the development of preeclampsia and fetal growth restriction (FGR). Recently, preeclampsia was linked to impaired maternal hemodynamic function. This retrospective study evaluated singleton pregnancies with COVID-19 during pregnancy and [...] Read more.
Infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) in pregnancy are associated with the development of preeclampsia and fetal growth restriction (FGR). Recently, preeclampsia was linked to impaired maternal hemodynamic function. This retrospective study evaluated singleton pregnancies with COVID-19 during pregnancy and healthy pregnant controls matched for gestational age from November 2020 to March 2022. Non-invasive assessment of maternal hemodynamics by continuous wave Doppler ultrasound measurements (USCOM-1A® Monitor) and oscillometric arterial stiffness (Arteriograph) was performed. Overall, 69 pregnant women were included—23 women after COVID-19 during pregnancy and 46 healthy controls. While two women (8.7%) were admitted to the hospital due to COVID-19-related symptoms, none required intensive care unit admission or non-invasive/invasive ventilation. There were no statistically significant differences in the majority of hemodynamic parameters between the two cohorts. The prevalence of FGR was significantly higher in the COVID-19 during pregnancy group (9.5% vs. healthy controls: 0.0%; p = 0.036), especially in nulliparous women. No difference in angiogenic markers and neonatal outcomes were observed between pregnant women after COVID-19 and healthy controls. In conclusion, no significant differences in hemodynamic parameters or neonatal outcome were observed in women with COVID-19 during pregnancy. However, an increased prevalence of FGR could be described. Full article
(This article belongs to the Special Issue COVID-19 Complications and Co-infections)
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