In Vitro and In Vivo Imaging-Based Evaluation of Doxorubicin Anticancer Treatment in Combination with the Herbal Medicine Black Cohosh
Abstract
:1. Introduction
2. Results
2.1. Results of In Vitro Studies
2.2. Results of In Vivo Studies
2.3. Results of Ex Vivo Studies
3. Discussion
4. Materials and Methods
4.1. In Vitro Studies
4.1.1. Cell Culture
4.1.2. Cell Viability Studies
4.1.3. Flow Cytometric Analysis of Apoptosis and Necrosis
4.1.4. Cell Survival Studies
4.1.5. Doxorubicin Efflux Studies
4.2. In Vivo Studies
4.2.1. In Vivo Imaging of MCF-7 Xenografts
4.2.2. Image Analysis
4.3. Ex Vivo Studies
4.4. Statistical Analysis
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Płoska, A.; Wozniak, M.; Hedhli, J.; Konopka, C.J.; Skondras, A.; Matatov, S.; Stawarz, A.; Schuh, S.; Czerwinski, A.; Dobrucki, L.W.; et al. In Vitro and In Vivo Imaging-Based Evaluation of Doxorubicin Anticancer Treatment in Combination with the Herbal Medicine Black Cohosh. Int. J. Mol. Sci. 2023, 24, 17506. https://doi.org/10.3390/ijms242417506
Płoska A, Wozniak M, Hedhli J, Konopka CJ, Skondras A, Matatov S, Stawarz A, Schuh S, Czerwinski A, Dobrucki LW, et al. In Vitro and In Vivo Imaging-Based Evaluation of Doxorubicin Anticancer Treatment in Combination with the Herbal Medicine Black Cohosh. International Journal of Molecular Sciences. 2023; 24(24):17506. https://doi.org/10.3390/ijms242417506
Chicago/Turabian StylePłoska, Agata, Marcin Wozniak, Jamila Hedhli, Christian J. Konopka, Antonios Skondras, Sarah Matatov, Andrew Stawarz, Sarah Schuh, Andrzej Czerwinski, Lawrence W. Dobrucki, and et al. 2023. "In Vitro and In Vivo Imaging-Based Evaluation of Doxorubicin Anticancer Treatment in Combination with the Herbal Medicine Black Cohosh" International Journal of Molecular Sciences 24, no. 24: 17506. https://doi.org/10.3390/ijms242417506