Editorial for the Special Issue “Hydrogels for 3D Printing”
- The review “Essential Guide to Hydrogel Rheology in Extrusion 3D Printing: How to Measure It and Why It Matters?” by Herrada-Manchón et al. examines the crucial role of rheology in extrusion-based 3D printing, focusing on hydrogels and their applications in tissue engineering, regenerative medicine, and drug delivery. Understanding rheological properties such as shear-thinning behavior, thixotropy, and viscoelasticity is essential for optimizing the printing process and achieving the desired product quality.
- The review “3D-Printed Hydrogel for Diverse Applications: A Review” by Agrawal et al. explores the intersection of hydrogels and 3D printing, covering current research, technological advancements, and future directions in various applications, including biomedical engineering. It discusses hydrogel basics, materials, 3D printing methods, and challenges, in addition to predicting future trends.
- The review “Biopolymers for Tissue Engineering: Crosslinking, Printing Techniques, and Applications” by Patrocinio et al. explores the use of proteins and polysaccharides in bioprinting for tissue engineering, focusing on their biocompatibility, biodegradability, and biomimicry. It addresses challenges related to rheological behaviors and the need for modifications or crosslinking. The manuscript also discusses tissue engineering applications, crosslinking, and bioprinting techniques, aiming to achieve bioprinted structures mimicking extracellular matrix properties with good levels of printability and stability.
- The article “Microbial Polysaccharide-Based Formulation with Silica Nanoparticles; A New Hydrogel Nanocomposite for 3D Printing” by Marin et al. develops printable hydrogel nanocomposites by adding silica nanoparticles to a microbial polysaccharide polymer network, aiming for biomedical applications. Their morpho-structural characteristics, swelling behavior, and mechanical stability were assessed, revealing excellent biocompatibility, making them suitable for regenerative medicine.
- The article “Three-Dimensional Printing of Red Algae Biopolymers: Effect of Locust Bean Gum on Rheology and Processability” by Oliveira et al. explores the extraction of gelling biopolymers from red seaweeds to produce sustainable food gels and assess their potential as bioinks for 3D printing, focusing on improving gel matrix definition through the addition of locust bean gum, as well as adjusting printing temperature.
- The article “A New Method for the Production of High-Concentration Collagen Bioinks with Semiautonomic Preparation” by Matejkova et al. introduces a novel method for preparing highly concentrated collagen bioinks, utilizing a two-step neutralization process based on bicarbonate buffering mechanisms and pH adjustment. The automated bioink preparation process ensures consistent quality, demonstrating sustained cell proliferation and viability, in addition to offering potential for advancing tissue engineering applications.
- The article “Alginate–Gelatin Hydrogel Scaffolds; An Optimization of Post-Printing Treatment for Enhanced Degradation and Swelling Behavior” by Kaliampakou et al. addresses the optimization of the post-printing treatment phase in 3D structure generation, focusing on enhancing scaffold degradation while maintaining targeted swelling behavior.
- The article “Characterization of Bioinks Prepared via Gelifying Extracellular Matrix from Decellularized Porcine Myocardia” by Sanz-Fraile et al. introduces a novel cardiac bioink derived exclusively from decellularized porcine myocardium and loaded with human-bone-marrow-derived mesenchymal stromal cells, eliminating the need for additional biomaterials or crosslinkers.
- The article “Role of pH and Crosslinking Ions on Cell Viability and Metabolic Activity in Alginate–Gelatin 3D Prints” by Souza et al. investigates the influence of pH and crosslinking ions on the stability, printability, and cell behavior of alginate–gelatin hydrogels commonly used in bioengineering. The results reveal that buffer pH and crosslinking ions affect the swelling and degradation rates of prints, as well as hydrogel printability.
- The article “Polydopamine Blending Increases Human Cell Proliferation in Gelatin–Xanthan Gum 3D-Printed Hydrogel” by Yerra et al. enhances the printability of gelatin–xanthan gum hydrogel by incorporating polydopamine (PDA), a mussel-inspired biopolymer, to create cell-laden 3D scaffolds demonstrating improved fibroblast and keratinocyte growth without affecting hydrogel characteristics, thereby suggesting its potential for developing innovative 3D-printed wound dressings.
Author Contributions
Acknowledgments
Conflicts of Interest
List of Contributions
- Herrada-Manchón, H.; Fernández, M.A.; Aguilar, E. Essential Guide to Hydrogel Rheology in Extrusion 3D Printing: How to Measure It and Why It Matters? Gels 2023, 9, 517. https://doi.org/10.3390/gels9070517.
- Agrawal, A.; Hussain, C.M. 3D-Printed Hydrogel for Diverse Applications: A Review. Gels 2023, 9, 960. https://doi.org/10.3390/gels9120960.
- Patrocinio, D.; Galván-Chacón, V.; Gómez-Blanco, J.C.; Miguel, S.P.; Loureiro, J.; Ribeiro, M.P.; Coutinho, P.; Pagador, J.B.; Sanchez-Margallo, F.M. Biopolymers for Tissue Engineering: Crosslinking, Printing Techniques, and Applications. Gels 2023, 9, 890. https://doi.org/10.3390/gels9110890.
- Marin, M.M.; Gifu, I.C.; Pircalabioru, G.G.; Albu Kaya, M.; Constantinescu, R.R.; Alexa, R.L.; Trica, B.; Alexandrescu, E.; Nistor, C.L.; Petcu, C.; et al. Microbial Polysaccharide-Based Formulation with Silica Nanoparticles; A New Hydrogel Nanocomposite for 3D Printing. Gels 2023, 9, 425. https://doi.org/10.3390/gels9050425.
- Oliveira, S.; Sousa, I.; Raymundo, A.; Bengoechea, C. Three-Dimensional Printing of Red Algae Biopolymers: Effect of Locust Bean Gum on Rheology and Processability. Gels 2024, 10, 166. https://doi.org/10.3390/gels10030166.
- Matejkova, J.; Kanokova, D.; Supova, M.; Matejka, R. A New Method for the Production of High-Concentration Collagen Bioinks with Semiautonomic Preparation. Gels 2024, 10, 66. https://doi.org/10.3390/gels10010066.
- Kaliampakou, C.; Lagopati, N.; Pavlatou, E.A.; Charitidis, C.A. Alginate–Gelatin Hydrogel Scaffolds; An Optimization of Post-Printing Treatment for Enhanced Degradation and Swelling Behavior. Gels 2023, 9, 857. https://doi.org/10.3390/gels9110857.
- Sanz-Fraile, H.; Herranz-Diez, C.; Ulldemolins, A.; Falcones, B.; Almendros, I.; Gavara, N.; Sunyer, R.; Farré, R.; Otero, J. Characterization of Bioinks Prepared via Gelifying Extracellular Matrix from Decellularized Porcine Myocardia. Gels 2023, 9, 745. https://doi.org/10.3390/gels9090745.
- Souza, A.; Parnell, M.; Rodriguez, B.J.; Reynaud, E.G. Role of pH and Crosslinking Ions on Cell Viability and Metabolic Activity in Alginate–Gelatin 3D Prints. Gels 2023, 9, 853. https://doi.org/10.3390/gels9110853.
- Yerra, P.; Migliario, M.; Gino, S.; Sabbatini, M.; Bignotto, M.; Invernizzi, M.; Renò, F. Polydopamine Blending Increases Human Cell Proliferation in Gelatin–Xanthan Gum 3D-Printed Hydrogel. Gels 2024, 10, 145. https://doi.org/10.3390/gels10020145.
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Aguilar, E.; Herrada-Manchón, H. Editorial for the Special Issue “Hydrogels for 3D Printing”. Gels 2024, 10, 323. https://doi.org/10.3390/gels10050323
Aguilar E, Herrada-Manchón H. Editorial for the Special Issue “Hydrogels for 3D Printing”. Gels. 2024; 10(5):323. https://doi.org/10.3390/gels10050323
Chicago/Turabian StyleAguilar, Enrique, and Helena Herrada-Manchón. 2024. "Editorial for the Special Issue “Hydrogels for 3D Printing”" Gels 10, no. 5: 323. https://doi.org/10.3390/gels10050323