Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Inflammatory Processes in Healthy and Diseased Brains
edited by
submission deadline 1 Jun 2024 | 1 articles | Viewed by 2336
Keywords: immune response; neurodegeneration; microglia; inflammation; lymphocytes
(This special issue belongs to the Section Cells of the Nervous System)
Metabolic Adaptation Processes in Cancer: Transcriptomic, Proteomic and Metabolomic Studies submission deadline 1 Jun 2024 | Viewed by 331
Keywords: cancer cell metabolism; inflammation; anticancer drugs; tumor-specific metabolic biomarkers; oxidative stress; omics sciences applied to cancer research; tumor immune microenvironment
(This special issue belongs to the Section Cellular Metabolism)
Gene and Cell Therapy in Regenerative Medicine—Second Edition submission deadline 10 Jun 2024 | 7 articles | Viewed by 9860 | Submission Open
Keywords: gene therapy; cell therapy; regenerative medicine; growth factors; stem cells
(This special issue belongs to the Section Cell and Gene Therapy)
Glioblastoma Cell: From Cellular and Molecular Mechanisms to Innovative Therapy
edited by
submission deadline 10 Jun 2024 | 3 articles | Viewed by 5150 | Submission Open
Keywords: glioblastoma cell line; adjuvant substance; target therapy; molecular pathways; molecular markers; GSCs
(This special issue belongs to the Section Cellular Pathology)
Liver Constituent Cells: Their Niche, Close Intercellular Relationship and Crosstalk with the Extracellular Environment—Current and Future Perspectives (2nd Edition) submission deadline 10 Jun 2024 | Viewed by 119 | Submission Open
Keywords: chronic liver diseases; liver microcirculatory milieu; liver sinusoidal endothelial cells (LSECs); hepatic stellate cells (HSCs); Kupffer cells; hepatocytes; cholangiocytes; sinusoid capillarization; Disse space
(This special issue belongs to the Section Tissues and Organs)
Review Papers in (Re)programming Cells for Cardiac Repair
edited by and
submission deadline 15 Jun 2024 | 4 articles | Viewed by 10883 | Submission Open
Keywords: cardiac programming; cardiogenesis; transcriptional regulation; epigenetics; cardiac tissue engineering
(This special issue belongs to the Section Cells of the Cardiovascular System)
Extracellular Vesicles in Health and Disease 2023 submission deadline 15 Jun 2024 | 5 articles | Viewed by 8473 | Submission Open
Keywords: extracellular vesicles; cancer; cardiovascular diseases; neurodegenerative diseases; autoimmunity and transplantation; innate immunity and inflammation; immunoregulation; infectious diseases
(This special issue belongs to the Section Cellular Pathology)
Hypothalamic Hormonal Secretion and Metabolism
edited by
submission deadline 15 Jun 2024 | 2 articles | Viewed by 4952 | Submission Open
Keywords: hypothalamus; endocrine control; energy homeostasis; hormones; signaling
(This special issue belongs to the Section Cellular Metabolism)
Forkhead-Box (Fox)O Family Transcription Factors in Cancer submission deadline 15 Jun 2024 | 1 articles | Viewed by 1516 | Submission Open
Keywords: forkhead-box class O transcription factors; cancer; apoptosis; tumor progression; EMT; gene transcription; drug resistance; endocrine therapy; lnRNA; PTMs
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Large-Scale Multi-Omic Approaches and Atlas-Based Profiling for Cellular, Molecular, and Functional Specificity, Heterogeneity, and Diversity in the Endocannabinoid System
edited by and
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1184 | Submission Open
Keywords: lipidomics; proteomics; transcriptomics; cluster analysis; massive parallel screening; molecular markers; brain circuits; development; neural plasticity; synapse; appetite and feeding behavior; addiction; pain; epilepsy; neurological disorders
(This special issue belongs to the Section Cells of the Nervous System)
Role of Autophagy in Plant Cells
edited by
submission deadline 15 Jun 2024 | Viewed by 368 | Submission Open
Keywords: autophagy; endoplasmic reticulum; TOR; vacuoles; lysosomes; mitochondria; plastids
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Epigenetics of Brain Function and Diseases submission deadline 15 Jun 2024 | Viewed by 341 | Submission Open
Keywords: neurodevelopmental; neurological; neuropsychiatric; and neurodegenerative disorders; DNA methylation; chromatin remodeling; histone modifications; non-coding RNA; transcriptome; epigenome; epigenetic writers; readers and erasers
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Melanoma and Non-melanoma Skin Cancer: Cellular Mechanisms, Immunity and Therapeutics
edited by
submission deadline 15 Jun 2024 | Viewed by 226 | Submission Open
Keywords: melanoma; squamous cell carcinoma; Merkel cell carcinoma; tumorigenicity; metastasis; therapeutic targets
(This special issue belongs to the Section Cellular Immunology)
Oxidative Stress in Aging and Neurodegenerative Diseases—Series 2
edited by
submission deadline 15 Jun 2024 | Viewed by 167 | Submission Open
Keywords: aging; oxidative stress; antioxidant; Alzheimer’ s disease; Parkinson’ s disease; Lou Gehrig’ s disease; drug discovery
(This special issue belongs to the Section Cellular Aging)
Tooth-Related Stem Cells and Regenerative Medicine
edited by and Masaki Honda
submission deadline 15 Jun 2024 | Viewed by 107 | Submission Open
Keywords: mesenchymal stem cells; neural crest cells; bone marrow; adipose tissue; cell proliferation; cell differentiation; signal transduction; extracellular matrix; growth factors; cell culture; scaffolds; cell sheets; preservation; transplantation; bone; dentin; cartilage; tooth; tissue engineering
(This special issue belongs to the Section Stem Cells)
Reprogrammed Cells in Disease Modeling and Drug Discovery II
edited by
submission deadline 20 Jun 2024 | 6 articles | Viewed by 10714 | Submission Open
Keywords: patient-derived cells; iPS (induced pluripotent stem cells); CRC (conditionally reprogrammed cells); organoids; air– liquid interface cultures; circulating tumor cells; human diseases; disease modeling; cancer models; drug discovery
(This special issue belongs to the Section Cell and Gene Therapy)
Molecular Mechanisms of Aging in Cardiovascular Disease
edited by Gloria Salazar
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1894 | Submission Open
Keywords: senescence; atherosclerosis; oxidative stress; inflammation
(This special issue belongs to the Section Cellular Pathology)
Advances in Hormonal Regulation of Calcium Homeostasis
edited by and Giulia Battafarano
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1347 | Submission Open
Keywords: calcium metabolism; vitamin D; parathyroid hormone; FGF23; pathology; translational medicine
Progress in Cancer Immunotherapies
edited by and Phuc Loi Luu
submission deadline 20 Jun 2024 | Viewed by 902 | Submission Open
Keywords: cancer immunotherapy; immune checkpoint inhibitors; personalized immunotherapy; tumor microenvironment; biomarkers in immunotherapy
(This special issue belongs to the Section Cellular Immunology)
Metabolic Regulation: Cell Growth and Proliferation—2nd Edition submission deadline 20 Jun 2024 | Viewed by 176 | Submission Open
Keywords: cancer; metabolic regulation; lactate; tumor stroma; fibroblasts; molecular signatures; mitochondria; metabolic biomarkers; animal model; tumorigenesis; metabolomics; transcriptomics; proteomics
Recent Advances in the Field of Metastatic Melanoma
edited by
submission deadline 25 Jun 2024 | 6 articles | Viewed by 7799 | Submission Open
Keywords: molecular mechanism; microenvironment; immune escape; metabolism reprograming; targeted therapy; immunotherapy; organoid and 3D culture; drug development
(This special issue belongs to the Section Cellular Pathology)
p53: State-of-the-Art in Revealing Cancer Targets
edited by and
submission deadline 25 Jun 2024 | Viewed by 213 | Submission Open
Keywords: mutant TP53; alternative splicing of p53; small p53 activators; post-translational modification; p53 interaction with partner protein; apoptosis and autophagy cross-talk; tumor microenvironment; immunotherapy
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Molecular and Cellular Basis of Atherosclerosis Development
edited by Wenduo Gu
submission deadline 25 Jun 2024 | Viewed by 112 | Submission Open
Keywords: atherosclerosis; endothelial cells; smooth muscle cells; adventitial fibroblasts; coronary artery diseases
(This special issue belongs to the Section Cells of the Cardiovascular System)
Innate Cellular Immunity in Xenotransplantation
edited by Ping Li
submission deadline 27 Jun 2024 | 1 articles | Viewed by 1476 | Submission Open
Keywords: innate immunity; natural killer cells; microphages; dendritic cells; neutrophils; xenotransplantation; immune rejection; immune tolerance; xenograft; genetic engineering
(This special issue belongs to the Section Cellular Immunology)
Signaling Regulation of Bone and Tooth Development
edited by Xiaofang Wang
submission deadline 28 Jun 2024 | Viewed by 129 | Submission Open
Keywords: bone; tooth; osteogenesis; odontogenesis; enamel; dentin; cementum; amelogenesis; dentinogenesis
Advances in Scanning Probe Microscopy in Cell Biology submission deadline 30 Jun 2024 | 12 articles | Viewed by 16278 | Submission Open
Autophagy in Kidney Homeostasis and Disease
edited by
submission deadline 30 Jun 2024 | 6 articles | Viewed by 14848 | Submission Open
Keywords: differentiation; endocytosis; macroautophagy; microautophagy; chaperone-mediated autophagy; metabolism; organelle quality control; oxidative stress; kidney cells; kidney disease
(This special issue belongs to the Section Autophagy)
Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis III
edited by
submission deadline 30 Jun 2024 | 6 articles | Viewed by 12916 | Submission Open
(This special issue belongs to the Section Tissues and Organs)
Advances in Allogeneic Cell Therapy
edited by
submission deadline 30 Jun 2024 | 5 articles | Viewed by 10981 | Submission Open
Keywords: hematopoietic stem cell; Chimeric Antigen Receptor (CAR); mesenchymal stem cell; immune modulation; engineering; expansion; processing; anti-tumor effect; graft-versus-tumor effect; histocompatibility
(This special issue belongs to the Section Cell and Gene Therapy)
Roles and Mechanisms of Ubiquitin Ligases (E3) and Deubiquitinases (DUBs)
edited by , Tsunehiro Mizushima and Hideki Yashiroda
submission deadline 30 Jun 2024 | 7 articles | Viewed by 8346 | Submission Open
Keywords: E3 ubiquitin ligases; deubiquitinases; ubiquitin; ubiquitination; proteasome
(This special issue belongs to the Section Cell Signaling)
Spotlight on Neuromuscular Diseases: Pathomechanisms and New Therapeutic Targets submission deadline 30 Jun 2024 | 5 articles | Viewed by 8266 | Submission Open
Keywords: neuromuscular disorders; myositis; myasthenia gravis; genetic mutations; muscle inflammation; de-/regeneration; immune cell infiltration; new therapy options; targeted therapy
(This special issue belongs to the Section Cellular Pathology)
Mechanism of Cell Signaling during Eye Development and Diseases submission deadline 30 Jun 2024 | 5 articles | Viewed by 8116 | Submission Open
Keywords: cell signaling; ocular; eye disorders; Wnt signaling; TGF-β
(This special issue belongs to the Section Cell Signaling)
Organ and Tissue Fibrosis: Molecular Signals and Cellular Mechanisms
edited by
submission deadline 30 Jun 2024 | 4 articles | Viewed by 6723 | Submission Open
Keywords: fibrosis; scarring; cytokine; myofibroblasts; extracellular matrix; growth factors; mesenchymal transition
(This special issue belongs to the Section Tissues and Organs)
Epigenetics in Plant Growth and in Response to Abiotic Stress
edited by Xuncheng Liu
submission deadline 30 Jun 2024 | 3 articles | Viewed by 5559 | Submission Open
Keywords: histone modification; DNA methylation; chromatin remodeling; transcription regulation; plant development
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Nuclear Pore Complex in Nanomedicine 2.0
edited by
submission deadline 30 Jun 2024 | 3 articles | Viewed by 5219 | Submission Open
Keywords: nuclear pore complexes; spider cobweb; tumor marker; LLPS; supply chain; nano-pores
(This special issue belongs to the Section Cell Microenvironment)
Understanding Spinal Cord Injury and Repair: From Molecules to Neurocircuits and Multimodal Prostheses
edited by
submission deadline 30 Jun 2024 | 4 articles | Viewed by 4619 | Submission Open
(This special issue belongs to the Section Cells of the Nervous System)
The Role of Androgen Receptor in Prostate Cancer—Revisited
edited by
submission deadline 30 Jun 2024 | 2 articles | Viewed by 3555 | Submission Open
Keywords: androgens; androgen receptor; prostate cancer; androgen deprivation therapy; castration resistance
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Changes in Thyrocytes during Thyroid Disease and Thyroid Cancer
edited by
submission deadline 30 Jun 2024 | 2 articles | Viewed by 3274 | Submission Open
Keywords: thyroid cancer; thyroid nodules; hypothyroidism; hyperthyroidism; immunogenetic markers; molecular pathways for autoimmune thyroid diseases; therapeutic approaches
(This special issue belongs to the Section Cellular Pathology)
Cytochrome C—Alternative Functions, New Interactions and Technological Applications submission deadline 30 Jun 2024 | 2 articles | Viewed by 2937 | Submission Open
Keywords: cytochrome c; proapoptotic activities; superoxide scavenging; peroxidase-like activity; mem-brane-permeabilizing activity; Raman spectroscopy; circular dichroism; aggregation; post-translational modifications; biosensor; bio-nanoelectronics
Tumor Immune Microenvironment for Effective Therapy II
edited by
submission deadline 30 Jun 2024 | 3 articles | Viewed by 2932 | Submission Open
Keywords: tumor microenvironment; cancer immunotherapy; immune checkpoints; immune cells; cancer-associated fibroblasts; vascular cells; inflammation; hypoxia; acidosis; cytokines
(This special issue belongs to the Section Cellular Pathology)
Molecular and Clinical Advances in Understanding Early Embryo Development—Volume II
edited by
submission deadline 30 Jun 2024 | 2 articles | Viewed by 2444 | Submission Open
Keywords: metabolism; biomembrane transport; genetics; epigenetic modifications; transgenerational inheritance; signaling; ART; in vitro culture; trophectoderm; inner cell mass
(This special issue belongs to the Section Reproductive Cells and Development)
New Discoveries in Dermatopathology: From Molecular Mechanisms to Therapeutic Opportunities
edited by and Gianluca Avallone
submission deadline 30 Jun 2024 | 2 articles | Viewed by 2168 | Submission Open
Keywords: dermatopathology; target therapy; molecular mechanism
(This special issue belongs to the Section Cellular Pathology)
Understanding the Extracellular Vesicles (EVs)-Mediated Horizontal Transfer of Non-coding RNAs submission deadline 30 Jun 2024 | 1 articles | Viewed by 2000 | Submission Open
Keywords: extracellular vesicles; non-coding RNA  ; horizontal transfer; RNA loading; RNA binding proteins
Aging in Neuronal Networks
edited by and Nuria García-Magro
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1998 | Submission Open
Keywords: synaptic plasticity; neuronal excitability; intracellular signaling; glia; neuroinflammation; cognitive decline
(This special issue belongs to the Section Cells of the Nervous System)
Genetic Disorders in Breast and Ovarian Cancer
edited by Marek Nowak and Miłosz Wilczyński
submission deadline 30 Jun 2024 | 2 articles | Viewed by 1981 | Submission Open
Keywords: ovarian cancer; breast cancer; oncogenesis; genetic disorders; targeted therapy
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
New Insights into Vascular Biology in Health and Disease
edited by Bashir M. Rezk
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1889 | Submission Open
Keywords: vascular diseases; cardiovascular; cancer; hyperhomocyteinemia; endothelial dysfunction; vascular smooth muscle cell; autophagy; alcohol; galectins; angiogenesis; neovascularization
(This special issue belongs to the Section Cells of the Cardiovascular System)
Evolutionary Impact of the Noncoding Genome in Higher Organisms – Recent Insights Obtained from the Molecular and Cellular Level to Systems Biology
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1685 | Submission Open
Keywords: cell biology immune cell functions immunogenetics noncoding genome neurobiology human evolution brain evolution brain-immune system interactions nucleic acid-based therapeutics RNA interference
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Head and Neck Cancer: From Mechanisms to Therapeutics
edited by , and Federica Ganci
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1632 | Submission Open
Keywords: immunotherapy; immune checkpoint; driver mutations; predictive factors; spatial gene expression analysis; single cell sequencing; epithelial‒mesenchymal transdifferentiation
(This special issue belongs to the Section Cellular Pathology)
Acute Kidney Injury: From Molecular Mechanisms to Diseases submission deadline 30 Jun 2024 | 1 articles | Viewed by 1612 | Submission Open
Keywords: acute kidney injury; mitochondrial dysfunction; signal pathways; metabolites
(This special issue belongs to the Section Tissues and Organs)
Impacts of X-chromosome Inactivation on Cell Function
edited by and
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1553 | Submission Open
Keywords: X-inactivation; sex-biases; cell differentiation; autoimmunity; cancer
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
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