Clinical Aspects of Diagnosis and Treatment of Endometriosis

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 25 October 2024 | Viewed by 456

Special Issue Editor


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Guest Editor
Department of Women’s Health Tübingen, Eberhard Karls University Tübingen, 72076 Tübingen, Germany
Interests: gynecologic oncology; endometriosis; surgery; basic and clinical research
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Special Issue Information

Dear Colleagues,

Endometriosis is a chronic gynecological disease affecting about 10% of women of childbearing age. It can affect various pelvic and abdominal organs and leads to a wide spectrum of symptoms including pain and infertility. Potential organ infiltration, e.g., into the ovaries, bowel, and bladder, can also lead to disfunction of affected organs. There are various hypotheses regarding the etiology, but this is still unclear. Endometriosis is characterized by the presence of endometrial-like tissue outside the uterus; these lesions are spread out in the abdominal cavity and differ in size. Superficial and deep infiltrating endometriosis is possible according to the type of organ or peritoneal infiltration.

The lesions can grow especially while pregnancy and relapses are possible. Medical or surgical therapy could be administered, while laparoscopy staging of endometriosis could be performed and the removal of endometriosis is possible to improve rate of fertility. Enzian classification is a tool for staging deep infiltrating endometriosis.

In recent years, the importance of economic, clinical and even diagnostic and therapeutic aspects is realized.

The aim of this Special Issue, entitled “Clinical Aspects of Diagnosis and Treatment of Endometriosis”, is to collect and publish original articles as well as reviews demonstrating advances in the diagnostic and therapeutic research field of endometriosis. In summary, better understanding in this field could also help clinicians better guide their patient toward suitable treatment decisions.

Dr. Cornelia Bachmann
Guest Editor

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Keywords

  • endometriosis
  • surgery
  • ultrasound-guided surgery
  • diagnosis
  • treatment
  • complications

Published Papers (1 paper)

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Research

10 pages, 439 KiB  
Article
Can Laparoscopic Surgery Reduce Fatigue in Women with Endometriosis?—A Pilot Study
by Theresa Reischer, Catherine Sklenar, Alexandra Perricos-Hess, Heinrich Husslein, Lorenz Kuessel, René Wenzl and Christine Bekos
J. Clin. Med. 2024, 13(11), 3150; https://doi.org/10.3390/jcm13113150 - 28 May 2024
Viewed by 226
Abstract
Background: Fatigue is mentioned as one of the most significant symptoms of endometriosis. The impact of laparoscopic endometriosis surgeries on fatigue remains unknown. The aim of this study was to investigate, for the first time, the effect of laparoscopic surgery in endometriosis patients, [...] Read more.
Background: Fatigue is mentioned as one of the most significant symptoms of endometriosis. The impact of laparoscopic endometriosis surgeries on fatigue remains unknown. The aim of this study was to investigate, for the first time, the effect of laparoscopic surgery in endometriosis patients, with the complete removal of endometriotic lesions, on the severity of fatigue. Methods: This is a single-center prospective pilot study including 58 participants. Participants were recruited at the Tertiary Endometriosis Referral Center of the Medical University of Vienna between February 2020 and November 2021. Thirty patients with histologically proven endometriosis were compared to a control group of 28 patients who underwent a laparoscopy for benign gynecologic conditions other than endometriosis. All participants were interviewed using the Fatigue Severity Scale before their surgery and 6 months afterward. Relationships between variables were established using regression analysis and associations were quantified as odds ratios. Results: Fatigue was significantly more severe preoperatively in patients with endometriosis when compared to controls ((odds ratio (OR): 1.82; 95% confidence interval (CI): 1.24–2.67, p < 0.01). Six months postoperatively, the fatigue severity score of endometriosis patients decreased significantly (p < 0.01). In multivariate analysis, fatigue was significantly associated with endometriosis (OR: 4.50, CI: 1.14–17.8, p < 0.05), when adjusted for abdominal pain and menstrual bleeding. Fatigue in patients with endometriosis was not associated with disease stage or the presence of deep endometriosis. Conclusions: Fatigue is a frequent and bothersome symptom in patients with endometriosis. Within our study, we demonstrated for the first time that fatigue responds to surgical treatment. The management of fatigue is crucial to improving patients’ quality of life. Full article
(This article belongs to the Special Issue Clinical Aspects of Diagnosis and Treatment of Endometriosis)
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