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Molecules 2012, 17(11), 13673-13686; doi:10.3390/molecules171113673
Article

Chemical Constituents from Stem Bark and Roots of Clausena anisata

1,2,* , 1
,
3
,
1
 and
2
1 Department of Chemistry, University of Douala, Cameroon, P.O. Box 24157, Douala, Cameroon 2 Department of Chemistry, Dalhousie University, 6274 Coburg Road, P.O. Box 15000, Halifax, NS B3H 4R2, Canada 3 Department of Organic Chemistry, University of Yaounde I, Cameroon, P.O. Box 812, Yaounde, Cameroon
* Author to whom correspondence should be addressed.
Received: 11 October 2012 / Revised: 14 November 2012 / Accepted: 15 November 2012 / Published: 20 November 2012
(This article belongs to the Section Natural Products)
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Abstract

Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-l-phenylalaninyl-N-benzoyl-l-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of these compounds were established by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HSQC, HMQC, HMBC and NOESY) spectroscopy and electrospray ionization mass spectrometry (MS).
Keywords: Rutaceae; Clausena anisata; stem bark and roots; carbazole alkaloids; peptide derivative; phytosterol Rutaceae; Clausena anisata; stem bark and roots; carbazole alkaloids; peptide derivative; phytosterol
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Songue, J.L.; Kouam; Dongo, E.; Mpondo, T.N.; White, R.L. Chemical Constituents from Stem Bark and Roots of Clausena anisata. Molecules 2012, 17, 13673-13686.

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