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Molecules 2012, 17(11), 13673-13686; doi:10.3390/molecules171113673

Chemical Constituents from Stem Bark and Roots of Clausena anisata

1
Department of Chemistry, University of Douala, Cameroon, P.O. Box 24157, Douala, Cameroon
2
Department of Chemistry, Dalhousie University, 6274 Coburg Road, P.O. Box 15000, Halifax, NS B3H 4R2, Canada
3
Department of Organic Chemistry, University of Yaounde I, Cameroon, P.O. Box 812, Yaounde, Cameroon
*
Author to whom correspondence should be addressed.
Received: 11 October 2012 / Revised: 14 November 2012 / Accepted: 15 November 2012 / Published: 20 November 2012
(This article belongs to the Section Natural Products)
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Abstract

Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-l-phenylalaninyl-N-benzoyl-l-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of these compounds were established by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HSQC, HMQC, HMBC and NOESY) spectroscopy and electrospray ionization mass spectrometry (MS).
Keywords: Rutaceae; Clausena anisata; stem bark and roots; carbazole alkaloids; peptide derivative; phytosterol Rutaceae; Clausena anisata; stem bark and roots; carbazole alkaloids; peptide derivative; phytosterol
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MDPI and ACS Style

Songue, J.L.; Kouam; Dongo, E.; Mpondo, T.N.; White, R.L. Chemical Constituents from Stem Bark and Roots of Clausena anisata. Molecules 2012, 17, 13673-13686.

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