Synthesis and Biological Activity Evaluation of Novel β-Substituted Nitromethylene Neonicotinoid Analogues
Abstract
:1. Introduction
2. Results and Discussion
2.1. Synthetic Chemistry
2.2. Biological Activities
Compounds | Mortality (%, 500mg L−1) | LC50 (mmol L−1) |
---|---|---|
7 | 100 | 0.01567 |
8 | 34.6 | nt a |
9 | 100 | 0.00974 |
10 | 0 | nt |
11 | 23.98 | nt |
12 | 100 | 0.02494 |
13 | 100 | 0.01893 |
14 | 87.82 | nt |
15 | 100 | 0.02677 |
16 | 32.4 | nt |
17 | 100 | 0.01778 |
18 | 16.19 | nt |
19 | 100 | 0.02200 |
20 | 100 | 0.02447 |
21 | 57.6 | nt |
22 | 100 | 0.11839 |
23 | 50.79 | nt |
3. Experimental
3.1. General
3.1.1. General Synthetic Procedure for 7–14
3.1.2. General Synthetic Procedure for 15–20
3.1.3. General Synthetic Procedure for 21–23
3.2. Biological Assay
4. Conclusions
Acknowledgments
References
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Wang, B.; Cheng, J.; Xu, Z.; Xu, X.; Shao, X.; Li, Z. Synthesis and Biological Activity Evaluation of Novel β-Substituted Nitromethylene Neonicotinoid Analogues. Molecules 2012, 17, 10014-10025. https://doi.org/10.3390/molecules170910014
Wang B, Cheng J, Xu Z, Xu X, Shao X, Li Z. Synthesis and Biological Activity Evaluation of Novel β-Substituted Nitromethylene Neonicotinoid Analogues. Molecules. 2012; 17(9):10014-10025. https://doi.org/10.3390/molecules170910014
Chicago/Turabian StyleWang, Baozhu, Jiagao Cheng, Zhiping Xu, Xiaoyong Xu, Xusheng Shao, and Zhong Li. 2012. "Synthesis and Biological Activity Evaluation of Novel β-Substituted Nitromethylene Neonicotinoid Analogues" Molecules 17, no. 9: 10014-10025. https://doi.org/10.3390/molecules170910014