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Molecules 2013, 18(1), 1181-1187; doi:10.3390/molecules18011181

Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect

School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China
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Received: 22 November 2012 / Revised: 25 December 2012 / Accepted: 8 January 2013 / Published: 17 January 2013
(This article belongs to the Section Natural Products)
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Abstract

Two cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods including IR, MS and NMR. Compound 1 exhibited moderate neuroprotective effect against SH-SY5Y cell damage induced by hydrogen peroxide.
Keywords: Sterculia lychnophora; constituents; cerebrosides; neuroprotective effect Sterculia lychnophora; constituents; cerebrosides; neuroprotective effect
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MDPI and ACS Style

Wang, R.-F.; Wu, X.-W.; Geng, D. Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect. Molecules 2013, 18, 1181-1187.

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