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Molecules 2013, 18(5), 4876-4886; doi:10.3390/molecules18054876
Article

Anti-Oxidative and Anti-Proliferative Activity on Human Prostate Cancer Cells Lines of the Phenolic Compounds from Corylopsis coreana Uyeki

, , , ,  and *
College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 4 January 2013 / Revised: 20 April 2013 / Accepted: 23 April 2013 / Published: 24 April 2013
(This article belongs to the Section Natural Products)
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Abstract

Fifteen phenolic compounds, including three caffeoyl derivatives, four gallotannins, three ellagitannins and five flavonoids, were isolated from an 80% MeOH extract of the leaves of Corylopsis coreana Uyeki (Korean winter hazel; CL). The anti-oxidative activities [1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and xanthine oxidase superoxide scavenging activities (NBT)] and the anti-proliferative activity on human prostate cancer cell lines (DU145 and LNCaP) were also evaluated.
Keywords: Corylopsis coreana. Uyeki; 1,1-diphenyl-2-picrylhydazyl radical; superoxide scavenging; LNCaP; DU145 Corylopsis coreana. Uyeki; 1,1-diphenyl-2-picrylhydazyl radical; superoxide scavenging; LNCaP; DU145
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Kim, M.H.; Ha, S.Y.; Oh, M.H.; Kim, H.H.; Kim, S.R.; Lee, M.W. Anti-Oxidative and Anti-Proliferative Activity on Human Prostate Cancer Cells Lines of the Phenolic Compounds from Corylopsis coreana Uyeki. Molecules 2013, 18, 4876-4886.

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