4-Aminobenzoic Acid-Coated Maghemite Nanoparticles as Potential Anticancer Drug Magnetic Carriers: A Case Study on Highly Cytotoxic Cisplatin-Like Complexes Involving 7-Azaindoles
Abstract
:1. Introduction
2. Results and Discussion
2.1. Preparation and Properties of PABA@FeNPs
2.2. Functionalization of PABA@FeNPs by Platinum(II) Complexes
2.3. Mössbauer Spectroscopy
Sample | Component | δ ± 0.01 (mm/s) | ΔEQ ± 0.01 (mm/s) | RA ± 1 (%) | Assignment |
---|---|---|---|---|---|
PABA@FeNPs | Doublet | 0.34 | 0.66 | 18 | Fe3+ relaxation component |
Singlet | 0.35 | 82 | Fe3+ superparamagnetic component | ||
2*PABA@FeNPs | Doublet | 0.35 | 0.69 | 88 | Fe3+ relaxation component |
Singlet | 0.35 | 78 | Fe3+ superparamagnetic component |
3. Experimental
3.1. Materials and Methods
3.2. PABA@FeNPs Nanoparticles
3.3. Synthesis of 1*@PABA@FeNPs and 2*@PABA@FeNPs
4. Conclusions
Supplementary Materials
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Štarha, P.; Stavárek, M.; Tuček, J.; Trávníček, Z. 4-Aminobenzoic Acid-Coated Maghemite Nanoparticles as Potential Anticancer Drug Magnetic Carriers: A Case Study on Highly Cytotoxic Cisplatin-Like Complexes Involving 7-Azaindoles. Molecules 2014, 19, 1622-1634. https://doi.org/10.3390/molecules19021622
Štarha P, Stavárek M, Tuček J, Trávníček Z. 4-Aminobenzoic Acid-Coated Maghemite Nanoparticles as Potential Anticancer Drug Magnetic Carriers: A Case Study on Highly Cytotoxic Cisplatin-Like Complexes Involving 7-Azaindoles. Molecules. 2014; 19(2):1622-1634. https://doi.org/10.3390/molecules19021622
Chicago/Turabian StyleŠtarha, Pavel, Martin Stavárek, Jiří Tuček, and Zdeněk Trávníček. 2014. "4-Aminobenzoic Acid-Coated Maghemite Nanoparticles as Potential Anticancer Drug Magnetic Carriers: A Case Study on Highly Cytotoxic Cisplatin-Like Complexes Involving 7-Azaindoles" Molecules 19, no. 2: 1622-1634. https://doi.org/10.3390/molecules19021622