Synthesis of New Active Sulfones in the 5-Nitroimidazole Series
Received: 29 March 2002 / Revised: 30 April 2002 / Accepted: 30 April 2002 / Published: 30 April 2002
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We describe here the preparation of new 5-nitroimidazoles which are known to have an efficacy against metronidazole-susceptible and -resistant Giarda
, and Entamoeba
spp. The multi-step synthesis uses electron transfer methodology.