Table of Contents
Int. J. Mol. Sci., Volume 17, Issue 11 (November 2016)
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Description Fireworks of p53 Proteoforms Illustrate the Protein Structure–Function Continuum Concept p53 is a [...] Read more. Fireworks of p53 Proteoforms Illustrate the Protein Structure–Function Continuum Concept p53 is a multifunctional protein with high intrinsic disorder content. It homotetramerizes, interacts with myriads of binding partners, contains numerous posttranslational modifications, has several isoforms, and is commonly mutated in cancers. Therefore, p53 serves as an illustration of the protein structure–function continuum concept, where generation of multiple proteoforms by various means define the ability of a protein to have a multitude of structurally and functionally different states. View this paper.