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Volume 2010
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Short Note

3-Hydroxy-4-{[(4-ethylphenyl)imino]methyl}phenyl Octadecanoate

by
Sie-Tiong Ha
1,*,
Jun-Kit Beh
2,
Yip-Foo Win
1 and
Siew-Teng Ong
1
1
Department of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Jln Universiti, Bandar Barat, 31900 Kampar, Perak, Malaysia
2
Department of Science, Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Jln Genting Jelang, Setapak, 53300 Kuala Lumpur, Malaysia
*
Author to whom correspondence should be addressed.
Molbank 2010, 2010(2), M681; https://doi.org/10.3390/M681
Submission received: 29 March 2010 / Accepted: 30 April 2010 / Published: 30 April 2010
Browse Figure
Versions Notes

Abstract

:
A new Schiff base ester, 3-hydroxy-4-{[(4-ethylphenyl)imino]methyl}phenyl octadecanoate, was synthesized and its IR, 1H NMR, 13C NMR and MS spectroscopic data are presented.

Graphical Abstract

The mesomorphic behavior of an organic compound is basically dependent on its molecular architecture in which a slight change in the molecular geometry brings about considerable change in its mesomorphic properties. Many mesogenic homologous series contain two central linkages, both of which may either be ester [1] or Schiff base (CH=N) linking groups [2] or one of which may be an ester and the other one a Schiff base [3]. Schiff base esters possessing a long alkyl chain have received overwhelming attention due to their possibility to show liquid crystallinity properties such as smectic and nematic phases [4,5,6,7].

Synthesis

4-Formyl-3-hydroxyphenyl octadecanoate was previously prepared via Steglich esterification [8]. In a round-bottom flask, a mixture of the aldehyde (1.74 g, 5.0 mmol), 4-ethylaniline (0.61 g, 5.0 mmol) and absolute ethanol (40 mL) was refluxed for 3h with stirring. The reaction mixture was filtered and the solvent was removed from the filtrate by evaporation. Recrystallization from absolute ethanol gave the title compound as a yellow solid (0.96 g, 39%).
Molbank 2010 m681 i001
Melting point: 86.2 oC
MS (EI): m/z = 507 (M+)
IR (KBr, cm-1): 3448 (O-H), 2955, 2917, 2848 (C-H aliphatic); 1758 (C=O ester); 1628 (C=N); 1607, 1472 (C=C aromatic).
1H NMR (400 MHz, CDCl3): δ/ppm 0.91 (t, 3H, J = 7.1 Hz, CH3), 1.27 (t, 3H, J = 7.3 Hz, Ar-CH2-CH3), 1.28-1.46 {m, 28H, CH3(CH2)14-}, 1.78 (quint, 2H, J = 7.5 Hz, -CH2CH2COO-), 2.58 (t, 2H, J = 7.4 Hz, -CH2COO-), 2.70 (q, 2H, J = 7.6 Hz, Ar-CH2CH3), 6.70 (dd, 1H, J = 2.2, 8.4 Hz, Ar-H), 6.77 (d, 1H, J = 2.2 Hz, Ar-H), 7.22-7.28 (m, 4H, Ar-H), 7.38 (d, 1H, J = 8.4 Hz, Ar-H), 8.63 (s, 1H, CH=N), 13.71 (s, 1H, OH).
13C NMR (100 MHz, CDCl3): δ/ppm 172.1 (COO), 161.2 (CH=N), 163.0, 154.8, 146.2, 143.8, 133.3, 129.2, 121.4, 117.6, 113.1, 110.8 (aromatic carbons), 34.9 (-CH2COO-), 25.3 (-CH2CH2COO-), 28.9 (Ar-CH2CH3), 32.3, 30.1, 30.0, 29.9, 29.8, 29.7, 29.6, 29.5, 23.1 (CH3(CH2)14-), 16.0 (Ar-CH2CH3), 14.5 (CH3(CH2)14).
Elemental analysis: Calculated for C33H49NO3 C, 78.06%, H, 9.73%, N, 2.76%; Found: C, 78.18%, H, 9.65%, N, 2.71%.

Supplementary materials

Supplementary File 1Supplementary File 2Supplementary File 3

Acknowledgments

The author (S.T. Ha) would like to thank Universiti Tunku Abdul Rahman for the financial support and research facilities.

References and Notes

  1. Ha, S.T.; Yeap, G.Y.; Boey, P.L. Synthesis and smectogenic A and C* properties of (S)-(-)-2-methylbutyl 4’-(4”-n-alkanoyloxybenzoyloxy)biphenyl-4-carboxylates. Int. J. Phys. Sci. 2010, 5, 182–191. [Google Scholar]
  2. Kelker, H.; Scheurle, B. A liquid crystalline (nematic) phase with a particularly low solidification point. Angew. Chem. Int. Edn. 1969, 884–885. [Google Scholar] [CrossRef]
  3. Dave, J.S.; Kurian, G. Mesomorphic Behaviour of Schiff Base Esters-I: (a) p(p'-n-Alkoxybenzoyloxy)benzylidene-p”-anisidines (b)p(p'-n-Alkoxybenzoyloxy)benzylidene-p”-toluidines. Mol. Cryst. Liq. Cryst. 1977, 42, 175–183. [Google Scholar] [CrossRef]
  4. Yeap, G.Y.; Ha, S.T.; Lim, P.L.; Boey, P.L.; Ito, M.M.; Sanehisa, S.; Youhei, Y. Synthesis, physical and mesomorphic properties of Schiff’s base esters containing ortho-, meta- and para-substituents in benzylidene-4’-alkanoyloxyanilines. Liq. Cryst. 2006, 33, 205–211. [Google Scholar] [CrossRef]
  5. Ha, S.T.; Ong, L.K.; Wong, J.P.W.; Yeap, G.Y.; Lin, H.C.; Ong, S.T.; Koh, T.M. Mesogenic Schiff's base ether with dimethylamino end group. Phase Transit. 2009, 82, 387–397. [Google Scholar] [CrossRef]
  6. Ha, S.T.; Ong, L.K.; Ong, S.T.; Yeap, G.Y.; Wong, J.P.W.; Koh, T.M.; Lin, H.C. Synthesis and mesomorphic properties of new Schiff base esters with different alkyl chains. Chin. Chem. Lett. 2009, 20, 767–770. [Google Scholar] [CrossRef]
  7. Ha, S.T.; Ong, L.K.; Yasodha, S.; Yeap, G.Y.; Boey, P.L.; Lin, H.C. New mesogenic Schiff base esters with polar chloro substituent: synthesis, thermotropic properties and X-ray diffraction studies. Am. J. Appl. Sci. 2010, 7, 214–220. [Google Scholar] [CrossRef]
  8. Ha, S.T.; Ong, S.T.; Chong, Y.T.; Yeap, G.Y. Synthesis of 4-{[(3-chlorophenyl)imino]methyl}-3-hydroxyphenyl myristate. Molbank 2009, 2009, M629. [Google Scholar] [CrossRef]

Share and Cite

MDPI and ACS Style

Ha, S.-T.; Beh, J.-K.; Win, Y.-F.; Ong, S.-T. 3-Hydroxy-4-{[(4-ethylphenyl)imino]methyl}phenyl Octadecanoate. Molbank 2010, 2010, M681. https://doi.org/10.3390/M681

AMA Style

Ha S-T, Beh J-K, Win Y-F, Ong S-T. 3-Hydroxy-4-{[(4-ethylphenyl)imino]methyl}phenyl Octadecanoate. Molbank. 2010; 2010(2):M681. https://doi.org/10.3390/M681

Chicago/Turabian Style

Ha, Sie-Tiong, Jun-Kit Beh, Yip-Foo Win, and Siew-Teng Ong. 2010. "3-Hydroxy-4-{[(4-ethylphenyl)imino]methyl}phenyl Octadecanoate" Molbank 2010, no. 2: M681. https://doi.org/10.3390/M681

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