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Molbank, Volume 2011, Issue 4 (December 2011) – 8 articles

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Research

83 KiB  
Short Note
4-Amino-N-(2-hydroxy-4-pentadecylbenzylidene)benzenesulfonamide
by Gadada Naganagowda and Amorn Petsom
Molbank 2011, 2011(4), M739; https://doi.org/10.3390/M739 - 13 Oct 2011
Cited by 2 | Viewed by 3636
Abstract
4-Amino-N-(2-hydroxy-4-pentadecylbenzylidene)benzenesulfonamide has been synthesized by reaction of 2-hydroxy-4-pentadecylbenzaldehyde with 4-aminobenzenesulfonamide in the presence of acetic acid in ethanol. The structure of this new compound was confirmed by elemental analysis, IR, 1H-NMR, 13C-NMR and mass spectral analysis. Full article
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175 KiB  
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N-(4-Methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximide
by Kavitha Kankanala, Varsha Prakash, Khagga Mukkanti, Vangala Ranga Reddy and Sarbani Pal
Molbank 2011, 2011(4), M740; https://doi.org/10.3390/M740 - 14 Oct 2011
Cited by 3 | Viewed by 4970
Abstract
The title compound, N-(4-methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximide was synthesized in high yield by reaction of N-(4-amino-2-phenoxyphenyl)methanesulfonamide and 9,10-dihydroanthracene-9,10-endo-α,β-succinic anhydride in glacial acetic acid. The structure of the compound was fully characterized by IR, 1H and 13C NMR, mass spectral analysis and elemental analysis. Full article
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191 KiB  
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2-(6-Methoxynaphthalen-2-yl)propionic acid (1,3-dimethyl­butylidene)hydrazide
by Nakka Mamatha, Nallapati Suresh Babu, Khagga Mukkanti and Sarbani Pal
Molbank 2011, 2011(4), M741; https://doi.org/10.3390/M741 - 18 Oct 2011
Cited by 7 | Viewed by 4303
Abstract
The title compound, 2-(6-methoxynaphthalen-2-yl)propionic acid (1,3-dimethyl­butylidene)hydrazide was synthesized in high yield by the reaction of 2-(6-methoxy­naphthalen-2-yl)propionic acid hydrazide and 4-methylpentan-2-one in PEG 400. This compound was fully characterized by IR, 1H NMR, mass spectra and elemental analysis. The in vitro antibacterial activity [...] Read more.
The title compound, 2-(6-methoxynaphthalen-2-yl)propionic acid (1,3-dimethyl­butylidene)hydrazide was synthesized in high yield by the reaction of 2-(6-methoxy­naphthalen-2-yl)propionic acid hydrazide and 4-methylpentan-2-one in PEG 400. This compound was fully characterized by IR, 1H NMR, mass spectra and elemental analysis. The in vitro antibacterial activity of this compound was evaluated against gram positive and gram negative bacteria. Full article
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174 KiB  
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3-[1-(4-Methylphenyl)-3-oxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl]propanoic Acid
by Ferenc Csende, József Jekő and Andrea Porkoláb
Molbank 2011, 2011(4), M742; https://doi.org/10.3390/M742 - 10 Nov 2011
Cited by 2 | Viewed by 4172
Abstract
A simple solvent-free synthesis of 3-[1-(4-methylphenyl)-3-oxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl]propanoic acid 3 was achieved by fusion of cis-2-[(4-methylphenyl)carbonyl]cyclohexanecarboxylic acid 1 with 3-aminopropanoic acid 2. The structure of this new compound was confirmed by elemental analysis, IR, EI-MS, 1H-NMR and 13C-NMR spectral data. Full article
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186 KiB  
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Ethyl (1,3-diphenyl-1H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetate
by Thoraya A. Farghaly and Sobhi M. Gomha
Molbank 2011, 2011(4), M743; https://doi.org/10.3390/M743 - 10 Nov 2011
Cited by 2 | Viewed by 3451
Abstract
Novel ethyl (1,3-diphenyl-1H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetate (5), was prepared via heating of 5-amino-1,3-diphenyl-4,5-dihydro-4-imino-1H-pyrazolo[3,4-d] pyrimidine (1) and diethyl malonate (2) under reflux. The structure of the synthesized compound was assigned on the basis of its elemental analysis, IR, 1H-NMR and mass spectral data. Full article
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161 KiB  
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1-(8-Chloro-3-methyl-1H-pyrazolo[4,3-c]cinnolin-1-yl)-2-(2-chlorophenyl)ethanone
by Sandhya Bawa, Rajiv K. Tonk, Gita Chawla, Suresh Kumar and Obaid Afzal
Molbank 2011, 2011(4), M744; https://doi.org/10.3390/M744 - 16 Nov 2011
Viewed by 3797
Abstract
1-(8-Chloro-3-methyl-1H-pyrazolo[4,3-c]cinnolin-1-yl)-2-(2-chlorophenyl)ethanone 2 has been synthesized through condensation of 3-acetyl-6-chloro-1H-cinnolin-4-one 1 with 2-(2-chlorophenyl)acetohydrazide in polar aprotic solvent containing catalytic amount of conc. HCl. The structure of the title compound 2 was established on the basis of IR, 1H-NMR, 13C-NMR and mass spectral data. Full article
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180 KiB  
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Ethyl 4,4''-Difluoro-5'-hydroxy-1,1':3',1''-terphenyl-4'-carboxylate
by Seranthimata Samshuddin, Badiadka Narayana and Balladka Kunhanna Sarojini
Molbank 2011, 2011(4), M745; https://doi.org/10.3390/M745 - 23 Nov 2011
Cited by 13 | Viewed by 4953
Abstract
A simple and novel route for the synthesis of new terphenyl derivative as well as oxidative aromatization of α,β-unsaturated cyclohexenone to the corresponding phenol derivative is developed. The present work involves the condensation of ethylacetoacetate with 4,4'-difluoro chalcone followed by the aromatization using [...] Read more.
A simple and novel route for the synthesis of new terphenyl derivative as well as oxidative aromatization of α,β-unsaturated cyclohexenone to the corresponding phenol derivative is developed. The present work involves the condensation of ethylacetoacetate with 4,4'-difluoro chalcone followed by the aromatization using chloramine-T in acetic acid to yield the title compound (3). The synthesized compound (3) is well characterized by IR, NMR, LCMS and elemental analysis. Full article
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120 KiB  
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(E)-Ethyl 3-(Dimethylamino)-2-(7,9-diphenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)acrylate
by Sobhi M. Gomha and Thoraya A. Farghaly
Molbank 2011, 2011(4), M746; https://doi.org/10.3390/M746 - 20 Dec 2011
Viewed by 3256
Abstract
Novel (E)-ethyl 3-(dimethylamino)-2-(7,9-diphenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)acrylate (3A), was prepared via condensation of ethyl (1,3-diphenyl-1H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetate (1) and dimethylformamide-dimethylacetal under reflux. The structure of the synthesized compound was assigned on the basis of elemental analysis, IR, 1H NMR and mass spectral data. Full article
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