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Molbank 2013, 2013(1), M794; doi:10.3390/M794

2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile

1
Chemistry of Pesticides Department, National Research Centre, Dokki, Cairo 12622, Egypt
2
Solid State Physics Department, National Research Centre, Dokki, Cairo 12622, Egypt
*
Author to whom correspondence should be addressed.
Received: 19 December 2012 / Accepted: 18 February 2013 / Published: 27 February 2013
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Abstract

2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile (4) was synthesized via nucleophilic substitution reaction of 1-methylpiperazine with 2-bromo analogue 3. The latter was obtained through bromination (Br2/AcOH) of 2-[3-oxo-1-phenyl-3-(thiophen-2-yl)propyl]malononitrile (2).
Keywords: 2-propen-1-one; pyridine-3-carbonitrile; single crystal X-ray 2-propen-1-one; pyridine-3-carbonitrile; single crystal X-ray
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MDPI and ACS Style

Mishriky, N.; Moustafa, A.M. 2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile. Molbank 2013, 2013, M794.

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