Investigation into the Effect of Varied Functional Biointerfaces on Silicon Nanowire MOSFETs
AbstractA biocompatible and functional interface can improve the sensitivity of bioelectronics. Here, 3-aminopropyl trimethoxysilane (APTMS) and 3-mercaptopropyl trimethoxysilane (MPTMS) self-assembled monolayers (SAMs) were independently modified on the surface of silicon nanowire metal-oxide-semiconductor field effect transistors (NW-MOSFETs). Those SAMs-modified silicon NW-MOSFETs were used to discriminate various pH solutions and further verify which modified regime was capable of providing better electrical signals. The APTMS-SAM modified NW-MOSFETs showed better electrical responses in pH sensing. Biomolecules on APTMS-SAM modified NW-MOSFETs also gave better signals for the corresponding proteind in physiological buffer solutions. Atomic force microscopy (AFM) clarified those electrical phenomena and found biomolecules on APTMS-SAM were relatively uniformly modified on NW-MOSFETs. Our results showed that more uniform modification contributed to better signal response to protein interactions in physiological buffer solutions. It suggests that suitable surface modifications could profoundly affect the sensing response and sensitivity. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Lin, S.-P.; Chi, T.-Y.; Lai, T.-Y.; Liu, M.-C. Investigation into the Effect of Varied Functional Biointerfaces on Silicon Nanowire MOSFETs. Sensors 2012, 12, 16867-16878.
Lin S-P, Chi T-Y, Lai T-Y, Liu M-C. Investigation into the Effect of Varied Functional Biointerfaces on Silicon Nanowire MOSFETs. Sensors. 2012; 12(12):16867-16878.Chicago/Turabian Style
Lin, Shu-Ping; Chi, Tien-Yin; Lai, Tung-Yen; Liu, Mao-Chen. 2012. "Investigation into the Effect of Varied Functional Biointerfaces on Silicon Nanowire MOSFETs." Sensors 12, no. 12: 16867-16878.