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Sensors, Volume 4, Issue 4 (April 2004), Pages 18-46

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Editorial

Jump to: Research

Open AccessEditorial New Editor-in-Chief of Sensors
Sensors 2004, 4(4), 18-19; doi:10.3390/s40400018
Received: 2 April 2004 / Published: 12 April 2004
PDF Full-text (30 KB) | HTML Full-text | XML Full-text

Research

Jump to: Editorial

Open AccessArticle Mathematical Model of the Biosensors Acting in a Trigger Mode
Sensors 2004, 4(4), 20-36; doi:10.3390/s40400020
Received: 12 March 2004 / Accepted: 10 May 2004 / Published: 26 May 2004
Cited by 8 | PDF Full-text (1065 KB) | HTML Full-text | XML Full-text
Abstract
A mathematical model of biosensors acting in a trigger mode has been developed. One type of the biosensors utilized a trigger enzymatic reaction followed by the cyclic enzymatic and electrochemical conversion of the product (CCE scheme). Other biosensors used the enzymatic trigger [...] Read more.
A mathematical model of biosensors acting in a trigger mode has been developed. One type of the biosensors utilized a trigger enzymatic reaction followed by the cyclic enzymatic and electrochemical conversion of the product (CCE scheme). Other biosensors used the enzymatic trigger reaction followed by the electrochemical and enzymatic product cyclic conversion (CEC scheme). The models were based on diffusion equations containing a non-linear term related to Michaelis-Menten kinetics of the enzymatic reactions. The digital simulation was carried out using the finite difference technique. The influence of the substrate concentration, the maximal enzymatic rate as well as the membrane thickness on the biosensor response was investigated. The numerical experiments demonstrated a significant gain (up to dozens of times) in biosensor sensitivity when the biosensor response was under diffusion control. In the case of significant signal amplification, the response time with triggering was up to several times longer than that of the biosensor without triggering. Full article
Open AccessArticle Temperature Gradient Effect on Gas Discrimination Power of a Metal-Oxide Thin-Film Sensor Microarray
Sensors 2004, 4(4), 37-46; doi:10.3390/s40400037
Received: 15 February 2004 / Accepted: 12 May 2004 / Published: 18 May 2004
Cited by 31 | PDF Full-text (283 KB) | HTML Full-text | XML Full-text
Abstract
The paper presents results concerning the effect of spatial inhomogeneous operating temperature on the gas discrimination power of a gas-sensor microarray, with the latter based on a thin SnO2 film employed in the KAMINA electronic nose. Three different temperature distributions over the [...] Read more.
The paper presents results concerning the effect of spatial inhomogeneous operating temperature on the gas discrimination power of a gas-sensor microarray, with the latter based on a thin SnO2 film employed in the KAMINA electronic nose. Three different temperature distributions over the substrate are discussed: a nearly homogeneous one and two temperature gradients, equal to approx. 3.3 oC/mm and 6.7 oC/mm, applied across the sensor elements (segments) of the array. The gas discrimination power of the microarray is judged by using the Mahalanobis distance in the LDA (Linear Discrimination Analysis) coordinate system between the data clusters obtained by the response of the microarray to four target vapors: ethanol, acetone, propanol and ammonia. It is shown that the application of a temperature gradient increases the gas discrimination power of the microarray by up to 35 %. Full article

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