Phakellistatins: An Underwater Unsolved Puzzle
AbstractA critical summary on the discovery of the nineteen members of the phakellistatin family (phakellistatin 1–19), cytotoxic proline-rich cyclopeptides of marine origin, is reported. Isolation, structural elucidation, and biological properties of the various-sized natural macrocycles are described, along with the total syntheses and the enigmatic issues of the cytotoxic activity reproducibility. View Full-Text
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Meli, A.; Tedesco, C.; Della Sala, G.; Schettini, R.; Albericio, F.; De Riccardis, F.; Izzo, I. Phakellistatins: An Underwater Unsolved Puzzle. Mar. Drugs 2017, 15, 78.
Meli A, Tedesco C, Della Sala G, Schettini R, Albericio F, De Riccardis F, Izzo I. Phakellistatins: An Underwater Unsolved Puzzle. Marine Drugs. 2017; 15(3):78.Chicago/Turabian Style
Meli, Alessandra; Tedesco, Consiglia; Della Sala, Giorgio; Schettini, Rosaria; Albericio, Fernando; De Riccardis, Francesco; Izzo, Irene. 2017. "Phakellistatins: An Underwater Unsolved Puzzle." Mar. Drugs 15, no. 3: 78.
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