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Materials 2017, 10(11), 1302; doi:10.3390/ma10111302

Antimicrobial and Osseointegration Properties of Nanostructured Titanium Orthopaedic Implants

1
Department of Orthopaedics and Trauma Surgery, University of Duisburg-Essen, Hufelandstrasse 55, D-45147 Essen, Germany
2
Institute of Physiological Chemistry, University Hospital, University of Duisburg Essen, Hufelandstrasse 55, D-45147 Essen, Germany
3
Institute of Metal Engineering, University of Duisburg-Essen, Campus Duisburg, Lotharstraße 1, D-47057 Duisburg, Germany
4
Institute of Medical Microbiology, University of Duisburg-Essen, Virchowstr. 179, D-45147 Essen, Germany
*
Author to whom correspondence should be addressed.
Received: 6 October 2017 / Revised: 1 November 2017 / Accepted: 8 November 2017 / Published: 13 November 2017
(This article belongs to the Section Biomaterials)
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Abstract

The surface design of titanium implants influences not only the local biological reactions but also affects at least the clinical result in orthopaedic application. During the last decades, strong efforts have been made to improve osteointegration and prevent bacterial adhesion to these surfaces. Following the rule of “smaller, faster, cheaper”, nanotechnology has encountered clinical application. It is evident that the hierarchical implant surface micro- and nanotopography orchestrate the biological cascades of early peri-implant endosseous healing or implant loosening. This review of the literature gives a brief overview of nanostructured titanium-base biomaterials designed to improve osteointegration and prevent from bacterial infection. View Full-Text
Keywords: nanostructure; implants; bone; antimicrobial; titanium; protein layer nanostructure; implants; bone; antimicrobial; titanium; protein layer
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MDPI and ACS Style

Jäger, M.; Jennissen, H.P.; Dittrich, F.; Fischer, A.; Köhling, H.L. Antimicrobial and Osseointegration Properties of Nanostructured Titanium Orthopaedic Implants. Materials 2017, 10, 1302.

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