Next Article in Journal
Vitamin A in Reproduction and Development
Next Article in Special Issue
Human Folate Bioavailability
Previous Article in Journal
Starches, Sugars and Obesity
Previous Article in Special Issue
Folate Production by Probiotic Bacteria
Article Menu

Export Article

Open AccessReview
Nutrients 2011, 3(3), 370-384; doi:10.3390/nu3030370

Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions

1
The Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30033, USA
2
The Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
*
Author to whom correspondence should be addressed.
Received: 27 January 2011 / Revised: 21 February 2011 / Accepted: 11 March 2011 / Published: 15 March 2011
(This article belongs to the Special Issue Folate Metabolism and Nutrition)
View Full-Text   |   Download PDF [206 KB, uploaded 15 March 2011]

Abstract

Periconceptional intake of folic acid is known to reduce a woman’s risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended consequences has led to concerns about higher folic acid intake and food fortification programs. This uncertainty emphasizes the need to continually monitor fortification programs for accurate measures of their effect and the ability to address concerns as they arise. This review highlights the history, effect, concerns, and future directions of folic acid food fortification programs.
Keywords: folic acid; flour fortification; neural tube defects; cancer; epigenetics folic acid; flour fortification; neural tube defects; cancer; epigenetics
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Crider, K.S.; Bailey, L.B.; Berry, R.J. Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions. Nutrients 2011, 3, 370-384.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top