Long-Term Consumption of Oats in Adult Celiac Disease Patients
AbstractMany celiac disease patients tolerate oats, but limited data are available on its long-term consumption. This was evaluated in the present study, focusing on small-bowel mucosal histology and gastrointestinal symptoms in celiac adults maintaining a strict gluten-free diet with or without oats. Altogether 106 long-term treated celiac adults were enrolled for this cross-sectional follow-up study. Daily consumption of oats and fiber was assessed, and small-bowel mucosal morphology and densities of CD3+, αβ+ and γσ+ intraepithelial lymphocytes determined. Gastrointestinal symptoms were assessed by a validated Gastrointestinal Symptom Rating Scale questionnaire. Seventy (66%) out of the 106 treated celiac disease patients had consumed a median of 20 g of oats (range 1–100 g) per day for up to eight years; all consumed oat products bought from general stores. Daily intake and long-term consumption of oats did not result in small-bowel mucosal villous damage, inflammation, or gastrointestinal symptoms. Oat-consumers had a significantly higher daily intake of fiber than those who did not use oats. Two thirds of celiac disease patients preferred to use oats in their daily diet. Even long-term ingestion of oats had no harmful effects.
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Kaukinen, K.; Collin, P.; Huhtala, H.; Mäki, M. Long-Term Consumption of Oats in Adult Celiac Disease Patients. Nutrients 2013, 5, 4380-4389.
Kaukinen K, Collin P, Huhtala H, Mäki M. Long-Term Consumption of Oats in Adult Celiac Disease Patients. Nutrients. 2013; 5(11):4380-4389.Chicago/Turabian Style
Kaukinen, Katri; Collin, Pekka; Huhtala, Heini; Mäki, Markku. 2013. "Long-Term Consumption of Oats in Adult Celiac Disease Patients." Nutrients 5, no. 11: 4380-4389.