Next Article in Journal
Iodine and Mental Development of Children 5 Years Old and Under: A Systematic Review and Meta-Analysis
Next Article in Special Issue
Echium Oil Reduces Plasma Triglycerides by Increasing Intravascular Lipolysis in apoB100-Only Low Density Lipoprotein (LDL) Receptor Knockout Mice
Previous Article in Journal
Selenium Supranutrition: Are the Potential Benefits of Chemoprevention Outweighed by the Promotion of Diabetes and Insulin Resistance?
Previous Article in Special Issue
Functionality of Fatty Acid Chemoreception: A Potential Factor in the Development of Obesity?
Nutrients 2013, 5(4), 1366-1383; doi:10.3390/nu5041366
Article

At-Risk Serum Cholesterol Profile at Both Ends of the Nutrition Spectrum in West African Adults? The Benin Study

1,* , 2,3
,
2,4
,
5
 and
6
1 TRANSNUT, WHO Collaborating Centre on Nutrition Changes and Development, Department of Nutrition, Faculty of Medicine, University of Montreal, PO Box 6128, Downtown Station, Montreal, QC H3C 3J7, Canada 2 TRANSNUT, Department of Nutrition, University of Montreal, PO Box 6128, Downtown Station, Montreal, QC H3C 3J7, Canada 3 Bioversity International, c/o IITA, 08 BP 0932 Cotonou, Benin 4 UNICEF-Chad, BP 1146, N'Djaména, Chad 5 Institute of Nutraceuticals and Functional Foods, Department of Food Science and Nutrition, Laval University, Quebec City, G1V 0A6, Canada 6 University Institute of Cardiology and Pneumology and Division of Kinesiology, Department of Social and Preventive Medicine, Laval University, Quebec City, G1V 0A6, Canada
* Author to whom correspondence should be addressed.
Received: 24 December 2012 / Revised: 27 February 2013 / Accepted: 28 March 2013 / Published: 19 April 2013
(This article belongs to the Special Issue Nutrition and Cardiovascular Diseases)
View Full-Text   |   Download PDF [499 KB, uploaded 19 April 2013]
SciFeed

Abstract

Low HDL-cholesterol (HDL-C), using as cut-offs 1.03 mmol/L in men and 1.29 mmol/L in women, was observed in more than 25% apparently healthy adults (n = 541) in a cross-sectional study on nutrition transition and cardiometabolic risk factors (CMRF) in Benin, West Africa. Both overweight/obesity (35.3%) and underweight (11.3%) were present, displaying the double burden of malnutrition. We examined in more depth the association of low HDL-C with nutrition and with other CMRF. Metabolic syndrome components were assessed, plus the ratio of total cholesterol (TC)/HDL-C and serum homocysteine. Insulin resistance was based on Homeostasis Model Assessment. We also measured BMI and body composition by bio-impedance. Dietary quality was appraised with two non-consecutive 24 h recalls. Low HDL-C was associated with much higher TC/HDL-C and more abdominal obesity in men and women and with more insulin resistance in women. The rate of low HDL-C was highest (41.9%) among the overweight/obese subjects (BMI ≥ 25), but it also reached 31.1% among the underweight (BMI < 18.5), compared with 17.3% among normal-weight subjects (p < 0.001). Lower dietary micronutrient adequacy, in particular, in vitamins A, B3, B12, zinc and calcium, was associated with low HDL-C when controlling for several confounders. This suggests that at-risk lipoprotein cholesterol may be associated with either underweight or overweight/obesity and with poor micronutrient intake.
Keywords: HDL-cholesterol; West Africa; metabolic syndrome; dietary quality; nutritional status; double burden of malnutrition; lifestyle; nutrition transition HDL-cholesterol; West Africa; metabolic syndrome; dietary quality; nutritional status; double burden of malnutrition; lifestyle; nutrition transition
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Delisle, H.; Ntandou, G.; Sodjinou, R.; Couillard, C.; Després, J.-P. At-Risk Serum Cholesterol Profile at Both Ends of the Nutrition Spectrum in West African Adults? The Benin Study. Nutrients 2013, 5, 1366-1383.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert