Micromachines 2013, 4(1), 103-115; doi:10.3390/mi4010103
Microbeads for Sampling and Mixing in a Complex Sample
1
Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332, USA
2
School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
3
Center for Food Safety, Department of Food Science & Technology, University of Georgia, Griffin, GA 30223, USA
*
Author to whom correspondence should be addressed.
Received: 21 January 2013 / Revised: 4 March 2013 / Accepted: 5 March 2013 / Published: 19 March 2013
(This article belongs to the Special Issue Selected Papers from the 1st International Conference on Microfluidic Handling Systems)
Abstract
This paper presents work on the development of a microfluidic device using super-paramagnetic beads for sampling and mixing. The beads are manipulated via an external rotating permanent magnet in a microfluidic channel. Efficient mixing is achieved in a short distance with this method. Modeling shows the variables which influence the mixing are flow rate, bead rotation speed and the bead number density. Displacement of the bead relative the rotating magnetic field sets an upper limit on the bead rotation speed due to viscous drag. Future work will examine optimization of this system for capture of pathogens from a complex mixture. View Full-TextKeywords:
microfluidics; convective mixing; magnetic microbeads; complex sample
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Owen, D.; Mao, W.; Alexeev, A.; Cannon, J.L.; Hesketh, P.J. Microbeads for Sampling and Mixing in a Complex Sample. Micromachines 2013, 4, 103-115.
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