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Polymers 2017, 9(3), 100; doi:10.3390/polym9030100

Antibacterial Property and Cytotoxicity of a Poly(lactic acid)/Nanosilver-Doped Multiwall Carbon Nanotube Nanocomposite

Material Corrosion and Protection Key Laboratory of Sichuan Province, College of Materials Science and Engineering, Sichuan University of Science and Engineering, Zigong 643000, China
Faculties of Biological and Chemical Engineering, Faculties of Materials Engineering, Science and Technology Innovation Center, Panzhihua University, Panzhihua 617000, China
Department of Materials Science, Chulalongkorn University, Bangkok 10330, Thailand
Department of Materials and Textiles, Oriental Institute of Technology, New Taipei City 22061, Taiwan
Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan
Faculty of Electronic and Electrical Engineering, Huaiyin Institute of Technology, Huan’an 223003, China
Department of Applied Cosmetology, Kao Yuan University, Kaohsiung 82101, Taiwan
Department of Molecular Science & Engineering, National Taipei University of Technology, Taipei 10608, Taiwan
Center for Membrane Technology, Chung Yuan University, Taoyuan 32023, Taiwan
Department of Fashion Business Administration, Lee-Ming Institute of Technology, Taishan, New Taipei City 24305, Taiwan
Authors to whom correspondence should be addressed.
Academic Editor: Naozumi Teramoto
Received: 17 November 2016 / Accepted: 8 March 2017 / Published: 10 March 2017
(This article belongs to the Special Issue Nanocomposites of Polymers and Inorganic Particles 2016)
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A novel method was used to synthesize a nanosilver-doped multiwall carbon nanotube (MWCNT-Ag), and subsequently, the novel poly(lactic acid) (PLA)- and MWCNT-Ag-based biocompatible and antimicrobial nanocomposites were prepared by melt blending. Based on energy dispersive X-ray spectrometry images, an MWCNT-Ag was successfully synthesized. The effect of the MWCNT-Ag on the PLA bionanocomposites was investigated by evaluating their thermal and mechanical properties, antifungal activity, and cytotoxicity. The nanocomposites exhibited a high degree of biocompatibility with the MWCNT-Ag content, which was less than 0.3 phr. Furthermore, tensile strength testing, thermogravimetric analysis, differential scanning calorimetry, and antibacterial evaluation revealed that the tensile strength, thermostability, glass transition temperature, and antibacterial properties were enhanced by increasing the MWCNT-Ag content. Finally, hydrolysis analysis indicated that the low MWCNT-Ag content could increase the packing density of PLA. View Full-Text
Keywords: poly(lactic acid); nanosilver-doped multiwall carbon nanotube; antibacterial property; cytotoxicity; bionanocomposites poly(lactic acid); nanosilver-doped multiwall carbon nanotube; antibacterial property; cytotoxicity; bionanocomposites

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Tsou, C.-H.; Yao, W.-H.; Lu, Y.-C.; Tsou, C.-Y.; Wu, C.-S.; Chen, J.; Wang, R.Y.; Su, C.; Hung, W.-S.; De Guzman, M.; Suen, M.-C. Antibacterial Property and Cytotoxicity of a Poly(lactic acid)/Nanosilver-Doped Multiwall Carbon Nanotube Nanocomposite. Polymers 2017, 9, 100.

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