Next Article in Journal
Quantification of Right and Left Ventricular Function in Cardiac MR Imaging: Comparison of Semiautomatic and Manual Segmentation Algorithms
Next Article in Special Issue
Induction of Anti-Tumor Immune Responses by Peptide Receptor Radionuclide Therapy with 177Lu-DOTATATE in a Murine Model of a Human Neuroendocrine Tumor
Previous Article in Journal / Special Issue
A Rapid, Multiplexed, High-Throughput Flow-Through Membrane Immunoassay: A Convenient Alternative to ELISA
Article Menu

Export Article

Open AccessArticle
Diagnostics 2013, 3(2), 261-270; doi:10.3390/diagnostics3020261

Computed Tomography (CT) Perfusion in Abdominal Cancer: Technical Aspects

Department of Diagnostic Radiology, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark
Metropolitan University College, Radiography Education, Sigurdsgade 26, Copenhagen 2200, Denmark
Department of Oncology, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark
Department of Cardiology, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark
Department of Surgery C, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark
Author to whom correspondence should be addressed.
Received: 18 February 2013 / Revised: 21 March 2013 / Accepted: 25 March 2013 / Published: 3 April 2013
(This article belongs to the Collection Feature Papers)
View Full-Text   |   Download PDF [533 KB, uploaded 9 April 2013]   |  


Computed Tomography (CT) Perfusion is an evolving method to visualize perfusion in organs and tissue. With the introduction of multidetector CT scanners, it is now possible to cover up to 16 cm in one rotation, and thereby making it possible to scan entire organs such as the liver with a fixed table position. Advances in reconstruction algorithms make it possible to reduce the radiation dose for each examination to acceptable levels. Regarding abdominal imaging, CT perfusion is still considered a research tool, but several studies have proven it as a reliable non-invasive technique for assessment of vascularity. CT perfusion has also been used for tumor characterization, staging of disease, response evaluation of newer drugs targeted towards angiogenesis and as a method for early detection of recurrence after radiation and embolization. There are several software solutions available on the market today based on different perfusion algorithms. However, there is no consensus on which protocol and algorithm to use for specific organs. In this article, the authors give an introduction to CT perfusion in abdominal imaging introducing technical aspects for calculation of perfusion parameters, and considerations on patient preparation. This article also contains clinical cases to illustrate the use of CT perfusion in abdominal imaging. View Full-Text
Keywords: CT Perfusion; cancer imaging; abdominal imaging; motion correction CT Perfusion; cancer imaging; abdominal imaging; motion correction

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Hansen, M.L.; Norling, R.; Lauridsen, C.; Fallentin, E.; Bæksgaard, L.; Kofoed, K.F.; Svendsen, L.B.; Nielsen, M.B. Computed Tomography (CT) Perfusion in Abdominal Cancer: Technical Aspects. Diagnostics 2013, 3, 261-270.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Diagnostics EISSN 2075-4418 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top