HIV DNA Vaccine: Stepwise Improvements Make a Difference
AbstractInefficient DNA delivery methods and low expression of plasmid DNA have been major obstacles for the use of plasmid DNA as vaccine for HIV/AIDS. This review describes successful efforts to improve DNA vaccine methodology over the past ~30 years. DNA vaccination, either alone or in combination with other methods, has the potential to be a rapid, safe, and effective vaccine platform against AIDS. Recent clinical trials suggest the feasibility of its translation to the clinic.
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Felber, B.K.; Valentin, A.; Rosati, M.; Bergamaschi, C.; Pavlakis, G.N. HIV DNA Vaccine: Stepwise Improvements Make a Difference. Vaccines 2014, 2, 354-379.
Felber BK, Valentin A, Rosati M, Bergamaschi C, Pavlakis GN. HIV DNA Vaccine: Stepwise Improvements Make a Difference. Vaccines. 2014; 2(2):354-379.Chicago/Turabian Style
Felber, Barbara K.; Valentin, Antonio; Rosati, Margherita; Bergamaschi, Cristina; Pavlakis, George N. 2014. "HIV DNA Vaccine: Stepwise Improvements Make a Difference." Vaccines 2, no. 2: 354-379.