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J. Funct. Biomater. 2012, 3(3), 688-705; doi:10.3390/jfb3030688

Biomimetic Strategies for Bone Repair and Regeneration

Institute of Composite and Biomedical Materials, National Research Council of Italy, P.le Tecchio 80, Naples 80125, Italy
Author to whom correspondence should be addressed.
Received: 29 May 2012 / Revised: 30 August 2012 / Accepted: 31 August 2012 / Published: 20 September 2012
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The osseointegration rate of implants is related to their composition and surface roughness. Implant roughness favors both bone anchoring and biomechanical stability. Osteoconductive calcium phosphate (Ca-P) coatings promote bone healing and apposition, leading to the rapid biological fixation of implants. It has been clearly shown in many publications that Ca-P coating accelerates bone formation around the implant. This review discusses two main routes for the manufacturing of polymer-based osteoconductive scaffolds for tissue engineering, namely the incorporation of bioceramic particles in the scaffold and the coating of a scaffold with a thin layer of apatite through a biomimetic process.
Keywords: biomimetic coating; bone substitute; hydroxyapatite; scaffold biomimetic coating; bone substitute; hydroxyapatite; scaffold
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Raucci, M.G.; Guarino, V.; Ambrosio, L. Biomimetic Strategies for Bone Repair and Regeneration. J. Funct. Biomater. 2012, 3, 688-705.

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