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Biosensors 2014, 4(1), 1-17; doi:10.3390/bios4010001

Application of a Nitric Oxide Sensor in Biomedicine

1
Instituto de Bioquímica, Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Edifício Egas Moniz, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal
2
Servico de Imunoalergologia, Centro Hospitalar Lisboa Norte-Hospital de Santa Maria, 1649-028 Lisboa, Portugal
*
Author to whom correspondence should be addressed.
Received: 19 December 2013 / Revised: 21 January 2014 / Accepted: 23 January 2014 / Published: 4 February 2014
(This article belongs to the Special Issue Sensors and Analytics for Cell Biology and Tissue Engineering)
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Abstract

In the present study, we describe the biochemical properties and effects of nitric oxide (NO) in intact and dysfunctional arterial and venous endothelium. Application of the NO electrochemical sensor in vivo and in vitro in erythrocytes of healthy subjects and patients with vascular disease are reviewed. The electrochemical NO sensor device applied to human umbilical venous endothelial cells (HUVECs) and the description of others NO types of sensors are also mentioned.
Keywords: endothelium erythrocyte nitric oxide; microelectrode endothelium erythrocyte nitric oxide; microelectrode
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Saldanha, C.; de Almeida, J.P.L.; Silva-Herdade, A.S. Application of a Nitric Oxide Sensor in Biomedicine. Biosensors 2014, 4, 1-17.

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