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Antibiotics 2013, 2(3), 339-351; doi:10.3390/antibiotics2030339

Empirical Antibiotic Therapy for Ventilator-Associated Pneumonia

1,*  and 2
1 College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Ave., Suite 203, Memphis, TN 38632, USA 2 Harrison School of Pharmacy, Auburn University, 1321 Walker Building, Auburn, AL 36849, USA
* Author to whom correspondence should be addressed.
Received: 2 April 2013 / Revised: 15 June 2013 / Accepted: 18 June 2013 / Published: 4 July 2013
(This article belongs to the Special Issue Antibiotics and Respiratory Tract Infections)
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Ventilator-associated pneumonia (VAP) is the most common infectious complication in the intensive care unit. It can increase duration of mechanical ventilation, length of stay, costs, and mortality. Improvements in the administration of empirical antibiotic therapy have potential to reduce the complications of VAP. This review will discuss the current data addressing empirical antibiotic therapy and the effect on mortality in patients with VAP. It will also address factors that could improve the administration of empirical antibiotics and directions for future research.
Keywords: empirical; antibiotic; ventilator-associated pneumonia empirical; antibiotic; ventilator-associated pneumonia
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Swanson, J.M.; Wells, D.L. Empirical Antibiotic Therapy for Ventilator-Associated Pneumonia. Antibiotics 2013, 2, 339-351.

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