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J. Dev. Biol. 2013, 1(2), 82-91; doi:10.3390/jdb1020082

Induction of the Proepicardium

University of California San Francisco, Cardiovascular Research Institute, San Francisco, CA 94143, USA
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Received: 4 June 2013 / Revised: 19 June 2013 / Accepted: 19 June 2013 / Published: 1 July 2013
(This article belongs to the Special Issue Epicardial Development and Cardiovascular Disease)
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Abstract

The proepicardium is a transient extracardiac embryonic tissue that gives rise to the epicardium and a number of coronary vascular cell lineages. This important extracardiac tissue develops through multiple steps of inductive events, from specification of multiple cell lineages to morphogenesis. This article will review our current understanding of inductive events involved in patterning of the proepicardium precursor field, specification of cell types within the proepicardium and their extension and attachment to the heart.
Keywords: cell fate induction; proepicardium field; epicardium cell fate induction; proepicardium field; epicardium
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Maya-Ramos, L.; Cleland, J.; Bressan, M.; Mikawa, T. Induction of the Proepicardium. J. Dev. Biol. 2013, 1, 82-91.

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