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Proteomes 2013, 1(1), 1-2; doi:10.3390/proteomes1010001

Proteomes: A New Proteomic Journal

Department of Proteomics and Signal Transduction, Max-Planck-Institute for Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany
Received: 22 October 2012 / Revised: 24 October 2012 / Accepted: 24 October 2012 / Published: 26 October 2012
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In the early years of proteomics, mass spectrometry served only as a technique in protein chemistry facilitating the characterization of purified proteins and mapping their posttranslational modifications (PTMs). A bit later this technique almost completely replaced Edman degradation and amino acid analysis. The continuous development of the mass spectrometry techniques created a huge analytical potential allowing the study of nearly complete proteomes in single experiments. This evolution distanced proteomics from protein chemistry and placed it in a novel position. Its capability to identify and quantify in parallel thousands of proteins and their modifications at minute sample amount requirements is one of the most fascinating technological advances in biology today. [...] View Full-Text
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Wiśniewski, J.R. Proteomes: A New Proteomic Journal. Proteomes 2013, 1, 1-2.

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