Table of Contents
Healthcare, Volume 5, Issue 2 (June 2017)
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Cover Story (view full-size image) Meta-analyses of epidemiological evidence showing no association between saturated fat and [...] Read more. Meta-analyses of epidemiological evidence showing no association between saturated fat and cardiovascular disease (CVD) have led to substantial controversy, and questions have been raised about whether saturated fat intake should be restricted to reduce CVD risk. These publications failed to consider the dietary replacements for saturated fat, a factor known to affect the observed association. In this paper, Briggs et al. compiled studies that investigated the cardiovascular impact of replacements for saturated fat. Consistent evidence showed that replacing saturated fat with sources of polyunsaturated fat and whole grains reduced CVD risk. Replacing saturated fat with plant-derived monounsaturated fat and plant protein also reduced CVD risk. However, replacement of saturated fat with refined carbohydrates conferred no benefit. To reduce CVD risk, saturated fat should be replaced with polyunsaturated fat, whole grains, plant-derived monounsaturated fat or plant protein.